The catalytic efficiency of METTL16 affects cellular processes by governing the intracellular S-adenosylmethionine setpoint. [PDF]
Flaherty JN +10 more
europepmc +1 more source
Neofunctionalization of S-adenosylmethionine decarboxylase into pyruvoyl-dependent L-ornithine and L-arginine decarboxylases is widespread in bacteria and archaea. [PDF]
Li B, Liang J, Phillips MA, Michael AJ.
europepmc +1 more source
Characterization of a full-length cDNA encoding human liver S-adenosylmethionine synthetase: tissue-specific gene expression and mRNA levels in hepatopathies [PDF]
Luis Álvarez +3 more
openalex +1 more source
0.15% GAA supplementation enhanced body weight and productive performance in heat‐stressed aged hens. Serum creatine, nitric oxide, and antioxidant capacity increased with GAA, while egg quality remained unaffected. One percent reduced protein diet with GAA maintained performance, whereas 2% reduction caused losses.
Reza Mahdavi +4 more
wiley +1 more source
S-adenosylmethionine metabolism buffering is regulated by a decrease in glycine N-methyltransferase via the nuclear ubiquitin-proteasome system. [PDF]
Kashio S, Miura M.
europepmc +1 more source
Gluconeogenic enzyme PCK1 supports S-adenosylmethionine biosynthesis and promotes H3K9me3 modification to suppress hepatocellular carcinoma progression. [PDF]
Gou D +11 more
europepmc +1 more source
YTHDC1 Orchestrates Telomerase Assembly via Scaffold‐Mediated TERT‐TERC Interaction
Schematic illustration of the major findings: METTL3‐deposited m6A modifications on TERC recruit the reader protein YTHDC1, which functions as a molecular scaffold to facilitate telomerase holoenzyme assembly by bridging TERT to m6A‐modified TERC transcripts, thereby promoting the proliferation of AECs.
Xiaolei Cheng +16 more
wiley +1 more source
S-adenosylmethionine metabolism shapes CD8<sup>+</sup> T cell functions in colorectal cancer. [PDF]
Yang X +5 more
europepmc +1 more source
Effects of S-Adenosylmethionine on Cognition in Animals and Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]
Zhao Y +9 more
europepmc +1 more source
S-adenosylmethionine (SAMe) in a feline acetaminophen model of oxidative injury [PDF]
CB Webb +3 more
openalex +1 more source

