Results 121 to 130 of about 18,351 (216)

Simultaneous Enantiomeric Separation and Binding Constants Determination by Affinity Capillary Electrophoresis using Human Serum Albumin [PDF]

, 2019
The binding of chiral drugs to plasma proteins is potentially enantioselective and frequently exhibits different pharmacological activities. Serum albumin is one of the most important proteins in human plasma and is commonly used as protein ligand in ...
Asmari, Mufarreh, Deeb, Sami El, Ratih, Ratih, Stein, Matthias   +3 more
core  

Machine Learning‐Based Prediction of Drug‐Induced QTc Changes in a Large Finnish Biobank Cohort

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Prolongation of the QT interval is a known precursor to serious arrhythmias and sudden cardiac death, often triggered by medication use. Current medication risk evaluation platforms rely on literature‐based synthesis and may lag behind real‐world developments.
Ville Langén, Aleksi Winstén, Konsta Teppo, Timo Pohjonen, Jari Laukkanen, Arto Mannermaa, Teemu J. Niiranen, Joonatan Palmu   +7 more
wiley   +1 more source

Transjugular Leadless Pacemaker Implantation in an Adolescent With Central Hypoventilation Syndrome: A Case Report

Pacing and Clinical Electrophysiology, Volume 49, Issue 5, Page 606-609, May 2026.
ABSTRACT Background Permanent pacing in pediatric patients is complicated by small body size, vascular access limitations, and the need for durable long‐term management. Leadless pacemakers offer an emerging alternative that minimizes infection and lead‐related complications, yet vascular access remains a key challenge in young patients.
Marzia Giaccardi, Gulio Porcedda, Zaccaria Ricci, Hendrik Bonnemeier, Benito Baldauf   +4 more
wiley   +1 more source

Comparative assessment of arterial stiffness and endothelial dysfunction during treatment with fixed combinations of antihypertensive drugs in patients with arterial hypertension and coronary artery disease

Consilium Medicum
Aim. To evaluate and compare the efficacy and safety of two triple fixed combinations (FC) of antihypertensive drugs, amlodipine/indapamide/perindopril and amlodipine/valsartan/hydrochlorothiazide (HCTZ), in managing the clinical course in patients with ...
Inara А. Khakuasheva, Murat A. Umetov, Janneta M. Urusbieva, Alena Kh. Abukova, Liana A. Didanova   +4 more
doaj   +1 more source

Bioequivalence study of S-amlodipine Gentisate Conventional Versus new Formulation [PDF]

Journal of Korean Society for Clinical Pharmacology and Therapeutics, 2008
Yun Jung Choi, Min Gul Kim, Bo-Hyung Kim, Kyung-Sang Yu, In-Jin Jang, Sang-Goo Shin   +5 more
openaire   +1 more source

Analysis of Adherence to Antihypertensive Drugs in Chinese Patients with Hypertension: A Retrospective Analysis Using the China Health Insurance Association Database 

Patient Preference and Adherence, 2020
Bin Cui,1 Zhaohui Dong,2 Mengmeng Zhao,3 Shanshan Li,4 Hua Xiao,4 Zhitao Liu,4 Xiaowei Yan5 1School of Public Health, Peking University, Beijing 100191, People’s Republic of China; 2Human Resources and Social Security, Chinese Academy of Labour and
Cui B, Dong Z, Zhao M, Li S, Xiao H, Liu Z, Yan X   +6 more
doaj  

RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF PHENYLEPHRINE HYDROCHLORIDE AND EBASTINE IN TABLET DOSAGE FORM [PDF]

, 2014
Objective: A new simple, accurate, precise, robust, reproducible and economic RP-HPLC method was developed for Phenylephrine Hydrochloride and Ebastine in marketed tablet dosage form.
Jain, Hemant Kumar, Yadav, Om M.
core  

DEVELOPMENT AND METHOD VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF CEFOPERAZONE AND TAZOBACTAM IN MARKETED FORMULATION [PDF]

, 2014
Objective: A new precise, accurate, sensitive and robust RP-HPLC method was developed for third generation cephalosporin and β lactamase inhibitor i.e. cefoperazone and tazobactam in marketed preparation.
Jain, Hemant Kumar, Ranjale, Amol R.
core  

What Lies Beyond the Thyroid? A Case of Neck Pain, Fever, and Hypertension

Journal of General and Family Medicine, Volume 27, Issue 3, May 2026.
Atsuhiko Sunaga, Takuya Inoue, Atsushi Omoto   +2 more
wiley   +1 more source

In Vivo Antimicrobial Activity of Nisin Z Against S. aureus and Polyurea Pharmadendrimer PURE_G4OEI₄₈ Against P. aeruginosa from Diabetic Foot Infections

Antibiotics
Background/Objectives: Diabetic foot infections (DFIs) are commonly associated with frequent hospitalizations, limb amputations, and premature death due to the profile of the bacteria infecting foot ulcers. DFIs are generally colonized by a polymicrobial
Isa Serrano, Dalila Mil-Homens, Rita F. Pires, Vasco D. B. Bonifácio, Joana F. Guerreiro, Eva Cunha, Sofia S. Costa, Luís Tavares, Manuela Oliveira   +8 more
doaj   +1 more source