Results 1 to 10 of about 4,911,014 (257)

Clinical Benefit of Fixed‐Dose Combination of Amlodipine and Potent Atorvastatin in Patients With Concomitant Hypertension and Hypercholesterolemia

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Hypertension and hypercholesterolemia are important risk factors for cardiovascular disease, and treatment with fixed‐dose combination (FDC) regimens is recommended by current guidelines. However, the clinical outcomes of different FDC dosages
Chia‐Pin Lin, Tzyy‐Jer Hsu, Ying‐Chang Tung, Fu‐Chih Hsiao, Shing‐Hsien Chou, Yu‐Sheng Lin, Shao‐Wei Chen, Pao‐Hsien Chu   +7 more
doaj   +3 more sources

Bioequivalence study of fixed-dose combination Losartan + amlodipine + rosuvastatin Sanofi in comparison with coadministered fixed- dose combination Lozap® AM and monocomponent drug Crestor® in healthy subjects

Фармакокинетика и Фармакодинамика, 2022
Introduction. The advantages of fixed-dose combination losartan + amlodipine + rosuvastatin compared to mono-drugs and two-component combinations are to increase the therapeutic efficacy, to reduce the cost of the product and to make the drug easier to ...
A. L. Khokhlov, D. Yu. Grebenkin, E. K. Faeva, V. I. Kazey, A. A. Khokhlov, A. E. Miroshnikov, O. V. Lebedeva   +6 more
doaj   +1 more source

Advantages of Efficacy and Safety of Fixed-Dose Tafluprost/Timolol Combination Over Fixed-Dose Latanoprost/Timolol Combination. [PDF]

PLoS ONE, 2016
To compare the safety and efficacy of fixed-dose tafluprost/timolol combination (Taf/T-FDC) with those of fixed-dose latanoprost/timolol combination (Lat/T-FDC) by measuring the intraocular pressure (IOP)-lowering effect, ocular pharmacokinetics, and ...
Masahiro Fuwa, Kenji Ueda, Takahiro Akaishi, Naoko Yamashita, Tomoko Kirihara, Atsushi Shimazaki, Hidetoshi Mano, Kouichi Kawazu   +7 more
doaj   +1 more source

The use of capillary electrophoresis in the simultaneous determination of fixed-dose combination drugs for cardiovascular diseases [PDF]

Trends in Pharmaceutical Sciences, 2020
Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide and are usually multifactorial medical conditions. Usually cardiovascular patients must follow a complicated treatment scheme, containing several drugs.
Gabriel Hancu, Daniela Tomegea, Gabriel Popescu, Eniko Barabas-Hajdu   +3 more
doaj   +1 more source

Optimization of Hypertension Treatment using Fixed-Dose Combination of Perindropril/Amlodipine

Majalah Kardiologi Indonesia, 2015
A lot of hypertensive patients require two or more antihypertensive drugs to control and maintain normal blood pressure. Combination of antihypertension is recommended either as first or second line treatment. Among available antihypertension medications,
Evan Hindoro, Arlis Karlina
doaj   +1 more source

Pharmacokinetics of a Fixed-Dose Combination Product of Dapagliflozin and Linagliptin and Its Comparison with Co-Administration of Individual Tablets in Healthy Humans

Pharmaceutics, 2022
Dapagliflozin, a selective sodium–glucose co-transporter-2 inhibitor, and linagliptin, a competitive, reversible dipeptidyl peptidase-4 inhibitor, are commonly prescribed antidiabetic medications in general clinics.
Jin-Woo Park, Jong-Min Kim, Ji Hyeon Noh, Kyoung-Ah Kim, Hyewon Chung, EunJi Kim, Minja Kang, Ji-Young Park   +7 more
doaj   +1 more source

An overview of fixed-dose combinations of antihypertensive drugs in South Africa

South African Family Practice, 2014
Hypertension is a pressing global health issue, contributing to an increase in cardiovascular risk, as well as being the most common condition seen in South Africa.
Natalie Schellack, Lucille Malan
doaj   +1 more source

Modern antihypertensive therapy: the effectiveness of a unique Russian fixed-dose combination of ramipril and indapamide

Российский кардиологический журнал, 2020
Experts consensus of the Russian Cardiology Society (RSC)
A. O. Konradi, S. V. Nedogoda, A. O. Nedoshivin, L. G. Ratova, R. A. Libis, G. P. Arutyunov, N. Yu. Borovkova, A. S. Galyavich, Yu. I. Grinshteyn, D. V. Duplyakov, V. V. Kashtalap, Yu. M. Lopatin, N. P. Lyamina, S. V. Malchikova, V. P. Mikhin, G. I. Nechaeva, O. D. Ostroumova, T. M. Ripp, G. A. Chumakova, I. I. Shaposhnik, V. V. Yakusevich   +20 more
doaj   +1 more source

Desenvolvimento e validação de método analítico para determinação simultânea de lamivudina, zidovudina e nevirapina em comprimidos dose-fixa combinada por cromatografia líquida de alta eficiência Development and validation of an analytical method for simultaneous determination of fixed-dose combination tablets of lamivudine, zidovudine and nevirapine by hight performance liquid chromatography

Química Nova, 2008
An analytical method has been developed and validated for the quantitation of lamivudine, zidovudine and nevirapine in the fixed-dose combination film-coated tablet by high performance liquid chromatography, in accordance with RE No.
Zênia Maria Maciel Lavra, Pedro José Rolim Neto, Rosali Maria Ferreira da Silva, Flávia Patrícia Morais de Medeiros   +3 more
doaj   +1 more source

A Comparative Evaluation of Ramipril as Monotherapy and Combination of Ramipril with Torsemide in Hypertension [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: A Fixed-Dose Combination (FDC) of antihypertensive agents of different groups might offer advantages of efficacy, tolerability and compliance over monotherapy.
Navjot Kaur, Ravinder Garg, Jasleen Kaur, Kamal Preet Palta, Mala Chandra, Shaminder Kaur, Ranabir Pal   +6 more
doaj   +1 more source