Results 1 to 10 of about 452,734 (338)

Triple fixed-dose combination empagliflozin, linagliptin, and metformin for patients with type 2 diabetes [PDF]

Postgraduate Medicine, 2020
Objectives Fixed-dose combination (FDC) therapy can improve outcomes in type 2 diabetes (T2D). We evaluated the bioequivalence of 2 doses of an FDC of extended-release metformin (metformin XR), empagliflozin, a sodium-glucose co-transporter 2 inhibitor ...
Ildikó Lingvay, Nadine Beetz, Regina Sennewald   +2 more
exaly   +3 more sources

Fixed-dose combination therapies with and without aspirin for primary prevention of cardiovascular disease: an individual participant data meta-analysis

Lancet, The, 2021
DigitalBackground In randomised controlled trials, fixed-dose combination treatments (or polypills) have been shown to reduce a composite of cardiovascular disease outcomes in primary prevention.
Philip Joseph, Gholamreza Roshandel, Peggy Gao   +2 more
exaly   +3 more sources

Treatment outcome in smear-positive pulmonary tuberculosis patients treated with a fixed-dose drug combination regimen in comparison with a separate regimen: a randomized clinical trial

Egyptian Journal of Chest Disease and Tuberculosis, 2021
Context The number of tuberculosis (TB) patients and multidrug-resistant species of Mycobacterium tuberculosis are increasing worldwide. Effective treatment is still the key factor to control TB in the society.
Seyed Saeed Hashemi Nazari, Saeid Fallah, Vahideh Raeisi   +2 more
doaj   +2 more sources

Regimen simplification and medication adherence: Fixed-dose versus loose-dose combination therapy for type 2 diabetes.

PLoS ONE, 2021
BackgroundSuboptimal patient adherence to pharmacological therapy of type 2 diabetes may be due in part to pill burden. One way to reduce pill burden in patients who need multiple medications is to use fixed-dose combinations.
Anna-Katharina Böhm, Udo Schneider, Jens Aberle, Tom Stargardt   +3 more
doaj   +2 more sources

Physicochemical Characterization of a Co-Amorphous Atorvastatin-Irbesartan System with a Potential Application in Fixed-Dose Combination Therapy [PDF]

Pharmaceutics, 2021
The aim of this study was to characterize a 1:1 molar ratio of a pharmacologically relevant co-amorphous atorvastatin-irbesartan (ATR-IRB) system obtained by quench cooling of the crystalline ATR/IRB physical mixture for potential use in the fixed-dose ...
Marcin Skotnicki, Barbara Jadach, Agnieszka Skotnicka, Bartłomiej Milanowski, Lidia Tajber, M. Pyda, Jacek Kujawski   +6 more
openalex   +2 more sources

Dyskalemia Prior to and After Initiation of a Fixed Dose Combination of Telmisartan and Amlodipine in Adults with Hypertension in Bangladesh [PDF]

Global Heart
Background: The World Health Organization recommends fixed-dose combination (FDC) pills for treating hypertension. Antihypertensive FDC pills often contain a renin-angiotensin inhibitor (RASI) or diuretic.
Junichi Ishigami, Md. Mahmudul Hasan, Aruna Sarker, Sharmin Nahar, Sibly Sadik Shuvo, Mir Ishraquzzaman, Mohammad Abdullah Al Mamun, Md. Kalimuddin, Sheikh Mohammad Mahbubus Sobhan, Di Zhao, Kunihiro Matsushita, Lawrence J. Appel, Sohel Reza Choudhury, Edgar R. Miller III, Fazila-Tun-Nesa Malik   +14 more
doaj   +2 more sources

Bempedoic acid plus ezetimibe fixed-dose combination in patients with hypercholesterolemia and high CVD risk treated with maximally tolerated statin therapy [PDF]

European Journal of Preventive Cardiology, 2019
Aims The aim of this study was to evaluate the low-density lipoprotein cholesterol lowering efficacy and safety of a bempedoic acid 180 mg and ezetimibe 10 mg fixed-dose combination in patients with hypercholesterolemia and a high risk of cardiovascular ...
Christie M. Ballantyne, Ulrich Laufs, Kausik K. Ray, Lawrence A. Leiter, Harold Bays, Anne C. Goldberg, Erik S.G. Stroes, Diane MacDougall, Xin Zhao, Alberico L. Catapano   +9 more
openalex   +2 more sources

Spillover adherence effects of fixed-dose combination HIV therapy

Patient Preference and Adherence, 2012
Teresa L Kauf1, Keith L Davis2, Stephanie R Earnshaw2, E Anne Davis31Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, FL, 2RTI Health Solutions, Research Triangle Park, NC, 3Independent consultant,
Kauf TL, Davis KL, Earnshaw SR, Davis EA
doaj   +1 more source

Repaglinide/metformin fixed-dose combination to improve glycemic control in patients with type 2 diabetes: an update

Diabetes, Metabolic Syndrome and Obesity, 2010
Robert G MosesClinical Trials and Research Unit, South East Sydney and Illawarra Area Health Service, New South Wales, AustraliaAbstract: Type 2 diabetes is a progressive disease associated with high levels of morbidity and mortality and for which there ...
Robert G Moses
doaj   +1 more source

Review of dutasteride/tamsulosin fixed-dose combination for the treatment of benign prostatic hyperplasia: efficacy, safety, and patient acceptability

Patient Preference and Adherence, 2011
Jack BarkinHumber River Regional Hospital, Toronto, Canada and Department of Surgery, University of Toronto, Toronto, Ontario, CanadaAbstract: Lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH) will usually affect older men,
Barkin J
doaj   +3 more sources