Results 191 to 200 of about 18,351 (216)

The impact of chirality on the development of robust and stable tablet formulation of (S-) amlodipine besylate

Pharmaceutical Development and Technology, 2013
The aim of this study was to compare the specific characteristics of the S-enantiomer and the racemate of amlodipine besylate (AB) in order to design a robust and stable formulation of the active S-enantiomer which will guarantee continuous performance of the unichiral version of amlodipine.
S, Hadžidedić, A, Uzunović, S, Sehić Jazić, S, Kocova El-Arini   +3 more
openaire   +2 more sources

S-amlodipine--the 2007 clinical review.

Journal of the Indian Medical Association, 2007
S-amlodipine is the only vaso-active enantiomer of amlodipine. This article reviews the published data in nearly 5000 patients. Randomised controlled trials of S-amlodipine at half the dose of racemate in the treatment of hypertension, have shown it to be as effective as racemic amlodipine.
openaire   +1 more source

[Organoprotective and metabolic effects of S-amlodipine in patients with arterial hypertension].

Kardiologiia, 2014
We compared effects of racemic amlodipine and S-amlodipine in 127 patients with 1-2 degree arterial hypertension (AH) on structural-functional parameters of the left ventricle and brachial artery as well as on characteristics of carbohydrate, lipid, electrolyte, and purine metabolism. Racemic amlodipine was given to 66 and S-amlodipine--to 61 patients.
B G, Iskenderov, S V, Saushkina
openaire   +1 more source

Pharmacological Evaluation of S-Amlodipine and Nimodipine as Bronchial Smooth Muscle Relaxants in Guinea Pigs:Ex-Vivo Study

Research Journal of Pharmacy and Technology
Background: S-amlodipine and Nimodipine, two members of the dihydropyridine calcium channel blocker family, were originally developed to treat cardiovascular disorders, and have shown significant potential in their ability to relax bronchial smooth muscle.
Kalabharathi . H.L, Prasad. C Reddy, Pushpa VH, Satish A M, Vidya G Doddawad   +4 more
openaire   +1 more source

Preparation of Carbon Fiber Composite Modified by Cobalt Lanthanum Oxides and its Electrochemical Simultaneous Determination of Amlodipine and Acetaminophen

Advanced Fiber Materials, 2022
Yaping Ding
exaly  

A3068 S-amlodipine improve endothelial dysfunction via RANK/RANKL/OPG pathway by targeting microRNA-155

Journal of Hypertension, 2018
Yang Jining, Daoyuan Si, Ping Yang
openaire   +1 more source

Amlodipine, an anti‐hypertensive drug, alleviates non‐alcoholic fatty liver disease by modulating gut microbiota

British Journal of Pharmacology, 2022
Lirui Wang
exaly  

Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial

Lancet, The, 2004
Michael A Weber, John Laragh, Alberto Zanchetti   +2 more
exaly  

SUBSTANTIATION OF THE DIRECT PRESS METHOD FOR S-AMLODIPINE NIKOTINATE TABLETS

"Medical & pharmaceutical journal "Pulse", 2020
openaire   +1 more source

Aliskiren and the calcium channel blocker amlodipine combination as an initial treatment strategy for hypertension control (ACCELERATE): a randomised, parallel-group trial

Lancet, The, 2011
Morris J Brown
exaly