Quantum chemistry calculation aided design of chiral ionic liquid-based extraction system for amlodipine separation [PDF]
, 2018 Amlodipine is a widely used medication in treating hypertension, which is also known as a chiral compound. So far efforts have been made to obtain optically pure (S)-amlodipine because (R)-amlodipine has poor efficacy and is ...
Becke +48 more
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Blood pressure control versus atrial fibrillation management in stroke prevention [PDF]
, 2015 Hypertension is one of the major risk factors for atrial fibrillation which in turn is the most prevalent concomitant condition in hypertensive patients. While both these pathological conditions are independent risk factors for stroke, the association of
Sada, Lidia +2 more
core +1 more source
The Effect of Visual Media Education in the Management Therapy on the Level of Knowledge of Patients Diabetes Mellitus with Comorbid [PDF]
, 2023 Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia that occurs due to abnormalities in insulin secretion, insulin action or both and is often accompanied by increased blood pressure.
Devi Ristian Octavia +1 more
core +2 more sources
Asymmetric addition of chiral boron-ate complexes to cyclic iminium ions [PDF]
, 2014 Boron-ate complexes derived from enantioenriched secondary benzylic boronic esters and aryl lithiums have been reacted with quinolinium, pyridinium and dihydroisoquinolinium salts to give enantioenriched heterocyclic structures with very high ...
Aggarwal, Varinder K. +4 more
core +2 more sources
Effects of S-Amlodipine in the Management of Hypertension in Mongolian Patients
Cardiology and Angiology: An International Journal, 2022 Objective: To evaluate the efficacy and safety of S-Amlodipine in patients suffering from hypertension. Materials and Methods: A multicenter, prospective, open-label, non-comparative, clinical trial was conducted on 364 patients with hypertension in Mongolia.
Namita Anchan +4 more
openaire +1 more source
Generic versus brand-name drugs used in cardiovascular diseases [PDF]
, 2016 This meta-analysis aimed to compare the efficacy and adverse events, either serious or mild/moderate, of all generic versus brand-name cardiovascular medicines.
Boccia, Stefania +9 more
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New cerebrovascular agent with hypotensive activity [PDF]
Research Results in Pharmacology, 2019 Introduction: In cerebrovascular disorders, special attention is paid to a hypertensive cerebrovascular crisis, which combines a vascular injury of the brain and hypertension.
Galina A. Kim +5 more
doaj +3 more sources
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, EarlyView.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Рациональная фармакотерапия в кардиологии, 2016 Aim. To evaluate efficacy and safety of a new drug of amlodipine – S-amlodipine (Azomex, Emcur, India) compared to original drug of racemic amlodipine (Norvasc, Pfizer, USA) in patients with arterial hypertension (HT) of I-II grade.Material and methods ...
M. A. Maksimova +5 more
doaj +1 more source
Pattern of adverse drug reactions reported at a tertiary health care teaching hospital of Tripura: a retrospective study [PDF]
, 2016 Background: ADR monitoring and reporting activity is in its infancy in India. India rates below 1% in pharmacovigilance as against the world rate of 5%. India is the fourth largest producer of pharmaceuticals in the world.
., Lalromawii +4 more
core +6 more sources