Separation of Chiral Compounds: Enantiomeric and Diastereomeric Mixtures [PDF]
Despite the dramatic development of enantioselective synthesis and chromatographic separation methods, optical resolution still remains the cheapest and operationally simplest method for producing pure enantiomers on a larger scale. No extreme conditions
Beáta, Szolnoki +4 more
core +1 more source
In vitro activity of non-antibiotic drugs against Staphylococcus aureus clinical strains
: Objectives: We hypothesised that one or more of the non-antibiotic candidates selected for this study would demonstrate antibiotic activity against Staphylococcus aureus.
Natalie K. Boyd +3 more
doaj +1 more source
The Effects of Amlodipine and S(-)-Amlodipine on Vascular Endothelial Function in Patients With Hypertension [PDF]
Amlodipine has been shown to improve vascular endothelial function in hypertensive patients, but whether S(-)-amlodipine has a similar effect remains controversial. This study compared the effects of amlodipine and S(-)-amlodipine on vascular endothelial function in hypertensive patients and investigated relevant mechanisms of action in cell culture ...
Yuquan, He +6 more
openaire +2 more sources
Adverse drug effects monitoring of amlodipine in a tertiary care hospital [PDF]
Background: Amlodipine have been widely used drug for the treatment of Hypertension. It has many beneficial effects and less side effects. But, only very few adverse effects of Amlodipine have been documented and many were not reported.
Kumar, C. Vinoth +2 more
core +2 more sources
Background: Chronic renin–angiotensin–aldosterone system (RAAS) activation is harmful. Amlodipine activates RAAS in humans and dogs, but contradictory data exist for systemically hypertensive (SHT) cats.
Darcy Adin +5 more
doaj +1 more source
Drug usage pattern of anti-hypertensive drugs in elderly diabetic, hypertensive in-patients with or without impaired renal function in a tertiary care hospital [PDF]
Background: Hypertension (HTN) and Diabetes mellitus (DM) are the leading contributors to the cardiovascular mortality and morbidity. Drug utilisation studies (DUS) are potential tools in the evaluation in health care systems.
Bhandary, Apeksha, R. Bhandari, Prasan
core +2 more sources
IN VITRO ASSESSMENT OF PHYSICOCHEMICAL PARAMETERS OF FIVE GENERICS AMLODIPINE BESYLATE TABLETS MARKETED IN YEMEN [PDF]
Objective: The present paper aims to evaluate the quality of five different brands (local and imported) of oral film-coated tablets of generic Amlodipine besylate 5 mg marketed in Sana`a-Yemen, through physiochemical parameters.
ALSHARGABI, ARWA
core +1 more source
Prescription pattern of fixed dose drug combination in cardiology department in a tertiary care hospital [PDF]
Background: A cardiovascular disease (CVD) is one of the most common causes of mortality and morbidity globally. The drastic change in the lifestyle of population during 21st century has had a great impact on health especially cardiovascular diseases ...
Dikshit, Harihar +6 more
core +2 more sources
Purpose In a randomised, double-blind trial, we investigated effects of lacidipine on clinic and ambulatory blood pressure (BP) and arterial stiffness in patients with mild-to-moderate hypertension, as compared with amlodipine.
Ying Wang +3 more
doaj +1 more source
Hao Liang,1,2,* Xinru Zhang,3,* Zhuo Ma,4,* Yan Sun,1,2 Chang Shu,1 Yihua Zhu,5,6 Yanwei Zhang,6 Songnian Hu,1,2 Xiujuan Fu,3 Lihong Liu4 1State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing ...
Liang H +9 more
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