Results 51 to 60 of about 234 (145)

Amlodipine Ameliorates Up-Regulation of ET-1 in Left Ventricle of Hypercholesterolemia Rabbits [PDF]

Iranian Journal of Basic Medical Sciences, 2010
Objective(s)In addition to antihypertensive effects, amlodipine may exhibit cardiovascular protective effects in heart tissue. The aim of this study was to evaluate the effects of amlodipine and/or high cholesterol diet on blood, heart tissue ...
Iraj Salehi, Safar Farajnia, Mustafa Mohammadi, Masoud Sabouri Ghannad   +3 more
doaj  

Melanopsin‐Mediated Post‐Illumination Pupillary Response in Idiopathic Rapid Eye Movement (REM) Sleep Behavior Disorder and Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Aims To conduct a case–control study to investigate melanopsin‐mediated post‐illumination pupillary response (PIPR) in patients with Parkinson's disease (PD), video‐polysomnography‐confirmed isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD), and age‐matched healthy controls (HC). Methods PIPR was measured at 6 s after
Joey W.Y. Chan, Bei Huang, Siyi Gong, Yuhua Yang, Shi Tang, Steven Wai‐ho Chau, Ngan Yin Chan, Tim Man‐ho Li, Yaping Liu, Anne Y.Y. Chan, Karen K.Y. Ma, Shirley X. Li, Joshua Tsoh, Kelvin K.L. Chong, Kathryn A. Roecklein, Vincent C.T. Mok, Yun Kwok Wing   +16 more
wiley   +1 more source

The translational potential of experimental pharmacology for cerebrovascular disorders

Анналы клинической и экспериментальной неврологии, 2019
The efficacy of reperfusion therapy to restore cerebral blood supply in patients with ischaemic cerebrovascular disorders is well recognized. Medications with proven cerebrovascular activity, such as oxymethylethylpyridine succinate (Mexidol), nicotinoyl-
Ruben S. Mirzoian, Tamara S. Gan’shina, Galina A. Kim, Elena V. Kurza, Denis V. Maslennikov, Il'ya N. Kurdyumov, Antonina I. Turilova, Aleksander A. Gorbunov   +7 more
doaj   +1 more source

Novel reference gene microseminoprotein‐beta based prostate cancer antigen 3 urine test: Enhanced diagnostic performance for prostate cancer and feasibility of non‐digital rectal examination urine sampling

UroPrecision, EarlyView.
Abstract Background The diagnosis of prostate cancer (PCa) is limited by low specificity and invasiveness. This study aims to establish a highly accurate, noninvasive reverse transcription‐quantitative polymerase chain reaction (RT‐qPCR)‐based urinary prostate cancer antigen 3 (PCA3) assay system and explore the feasibility of using first‐morning urine
Jianglei Xu, Lu Yang, Cong Shi, Yiwei Jiang, Jing Chen, Xiaoxiao Sun, Xuejuan Gao, Xian Wang, Jianzhong Jiang, Xiuzhi Duan, Xuchu Wang, Yiyi Xie, Zhixian Yu, Zhihua Tao, Xiaobing Dou, Chunyu Jin   +15 more
wiley   +1 more source

Renin-Angiotensin System Blockade Associated with Statin Improves Endothelial Function in Diabetics

Arquivos Brasileiros de Cardiologia, 2015
Background:Studies suggest that statins have pleiotropic effects, such as reduction in blood pressure, and improvement in endothelial function and vascular stiffness.Objective:To analyze if prior statin use influences the effect of renin-angiotensin ...
Ronaldo Altenburg Gismondi, Ricardo Bedirian, Cesar Romaro Pozzobon, Márcia Cristina Ladeira, Wille Oigman, Mário Fritsch Neves   +5 more
doaj   +1 more source

The dynamics of 24-hour ambulatory blood pressure monitoring parameters, subclinical damage and endothelial function of vessels in patients with arterial hypertension and chronic obstructive pulmonary disease treated with S-amlodipine, Nebivolol and Enala

Zaporožskij Medicinskij Žurnal, 2017
Aim of the research was to investigate additional prescription of S-amlodipine or Nebivolol to Enalapril treatment on the 24-h blood pressure monitoring (BPM) parameters, subclinical damage and endothelial function of vessels, and to make of proposing of
O. G. Ivanko, A. V. Tovma, A. V. Kamenshchyk, M. V. Patsera   +3 more
doaj   +1 more source

Insights from a six‐year hair drug analysis compendium in drug‐facilitated crimes involving vulnerable population cases

Journal of Forensic Sciences, EarlyView.
Abstract Hair analysis is a well‐established matrix in forensic toxicology, offering a valuable alternative or complement to traditional matrices in diverse contexts, including drug‐facilitated crimes (DFC), elder abuse, and accidental exposure in children.
Amandine Fort, Coralie Boudin, Hélène Eysseric‐Guerin, Virginie Scolan, François Paysant, Cloé Scherpereel, Mélissa Revet, Françoise Stanke‐Labesque, Théo Willeman   +8 more
wiley   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

TREATMENT OF ARTERIAL HYPERTENSION AND DYSLIPIDEMIA IN REAL CLINICAL PRACTICE. THE SYNERGY STUDY. Part 2

Рациональная фармакотерапия в кардиологии, 2017
Aim. To study the antihypertensive and hypolipidemic effect of therapy based on perindopril, including its combinations, and rosuvastatin in real clinical practice.Material and methods.
O. M. Drapkina, A. S. Luishuta
doaj   +1 more source