Results 61 to 70 of about 234 (145)
Biomedicine & Pharmacotherapy, 2019 S-amlodipine has been broadly used to treat hypertension, but its protective effects and underlying mechanism remain controversial. The purpose of our study was to investigate the mechanism by which S-amlodipine improves endothelial dysfunction. Specifically, we investigated if S-amlodipine regulates RANK/RANKL/OPG and micro-RNA 155 (miR-155) levels ...
Jining, Yang +4 more
openaire +2 more sources
National Journal of Physiology, Pharmacy and Pharmacology, 2018 Background: Calcium channel blockers (CCBs) are a commonly used class of drugs for the treatment of hypertension. Cilnidipine is a novel CCB with a dual L/N-type CCB property, thus favoring additional renal and cardiovascular protection.
Ajay D Shanbhag +2 more
doaj +1 more source
A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals
British Journal of Pharmacology, EarlyView.Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig +7 more
wiley +1 more source
Journal of Cardiovascular Electrophysiology, EarlyView.ABSTRACT Introduction Coronary vasospasm is a recognized complication of pulsed‐field ablation (PFA), but delayed events are rarely described. Methods and Results A 64‐year‐old man underwent atrial fibrillation ablation using a focal monopolar PFA catheter.
Yui Araki +3 more
wiley +1 more source
Risk Factors and Management of Gingival Enlargement: A Systematic Review and Meta‐Analysis
Journal of Clinical Periodontology, EarlyView.ABSTRACT Objective To identify risk factors/indicators of gingival enlargement (GE) and to summarise evidence for its management. Methods A systematic review was undertaken following PRISMA guidelines and divided into PECOTS and PICOTS questions, related to risk factors/indicators and treatment studies, respectively.
Luigi Nibali +5 more
wiley +1 more source
Journal of Periodontal Research, EarlyView.Resveratrol in repeated doses has been shown to suppress excessive cell proliferation without cytotoxic effects in amlodipine‐induced gingival hyperplasia, while not having a negative effect on mediators involved in tissue homeostasis in healthy cells, and at the same time, it reduces the expression of biomarkers involved in fibrosis processes ...
Bilkan Kara +6 more
wiley +1 more source
, 2018 SPIRIT 2013 checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 124Â kb)
Jo, Sang-Ho +10 more
openaire +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Loading Amlodipine on Diamond Nanoparticles: A Novel Drug Delivery System
Nanotechnology, Science and Applications, 2020 Shawqi H Alawdi,1,2 Housam Eidi,3 Marwa M Safar,4,5 Mosaad A Abdel-Wahhab6 1Department of Pharmacology, Faculty of Medicine and Health Sciences, Thamar University, Dhamar, Yemen; 2Department of Pharmacy Practice, Faculty of Pharmacy, University of ...
Alawdi SH +3 more
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