Results 81 to 90 of about 18,351 (216)

Use of Forced Degradation Studies on S-(−)-Amlodipine Besylate to Generate Information on the Degradation Products [PDF]

open access: yesScientia Pharmaceutica, 2010
Amlodipine is a long-acting calcium channel blocker used in the treatment of hypertension and angina pectoris. [...]
openaire   +1 more source

Recent advances in smart integrated membrane assisted liquid extraction technology [PDF]

open access: yes, 2017
Novel processes based on SIMALE have been proposed as effective methods for the selective separation of different chemical species such as metal ions, organic/biologically important compounds and gas mixtures from different waste streams including ...
Pabby, Anil Kumar   +2 more
core   +2 more sources

A quad‐cistronic fluorescent biosensor system for real‐time detection of subcellular Ca2+ signals

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose The calcium ion (Ca2+) is a versatile cellular messenger regulating a variety of biological processes. Compounds modulating subcellular Ca2+ signals hold substantial pharmacological potential. Advances in fluorescent biosensors have revolutionised Ca2+ imaging.
Anna Lischnig   +7 more
wiley   +1 more source

The development of type 2 diabetes amongst sibling pairs in the South‐South region of Nigeria: The effect of genetics, environment and lifestyle

open access: yesDiabetic Medicine, EarlyView.
Abstract Introduction Type 2 diabetes is a complex condition with a multifactorial pathogenesis. The pathogenesis is considered to be polygenic due to complex interactions between genetic/epigenetic and environmental factors. The aim of this study is to determine the genetic, environmental and lifestyle factors associated with the development of type 2
Sunny Chinenye   +18 more
wiley   +1 more source

TREATMENT OF ARTERIAL HYPERTENSION AND DYSLIPIDEMIA IN REAL CLINICAL PRACTICE. THE SYNERGY STUDY. Part 2

open access: yesРациональная фармакотерапия в кардиологии, 2017
Aim. To study the antihypertensive and hypolipidemic effect of therapy based on perindopril, including its combinations, and rosuvastatin in real clinical practice.Material and methods.
O. M. Drapkina, A. S. Luishuta
doaj   +1 more source

Tolerability and effectiveness of (S)-amlodipine compared with racemic amlodipine in hypertension: A systematic review and meta-analysis

open access: yesCurrent Therapeutic Research, 2010
Amlodipine is a calcium channel blocker prescribed for the management of angina and hypertension. As a racemic mixture, amlodipine contains (R)- and (S)-amlodipine isomers, but only (S)-amlodipine as the active moiety possesses therapeutic activity. Based on pharmacologic research, it remains uncertain if (S)-amlodipine alone has similar efficacy and ...
Liu, Fang, Qiu, Meng, Zhai, Suo-Di
openaire   +2 more sources

HPLC method development for the simultaneous analysis of amlodipine and valsartan in combined dosage forms and in vitro dissolution studies [PDF]

open access: yes, 2010
A simple, rapid and reproducible HPLC method was developed for the simultaneous determination of amlodipine and valsartan in their combined dosage forms, and for drug dissolution studies.
Altı   +3 more
core   +4 more sources

Perspectives of Older Patients on the Complexity of Medication Use

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Medication use complexity is associated with non‐adherence, hospitalizations, and lower quality of life. It is most frequently measured with the Medication Regimen Complexity Index (MRCI). This instrument estimates the complexity of a patient's medication regimen, taking into account the pharmaceutical dosage forms and routes ...
Charlotte M. Falke   +6 more
wiley   +1 more source

A randomized open-label study to compare the effects of amlodipine and cilnidipine on heart rate and proteinuria in subjects with hypertension with proteinuria

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2018
Background: Calcium channel blockers (CCBs) are a commonly used class of drugs for the treatment of hypertension. Cilnidipine is a novel CCB with a dual L/N-type CCB property, thus favoring additional renal and cardiovascular protection.
Ajay D Shanbhag   +2 more
doaj   +1 more source

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