Results 71 to 80 of about 18,351 (216)

Novel reference gene microseminoprotein‐beta based prostate cancer antigen 3 urine test: Enhanced diagnostic performance for prostate cancer and feasibility of non‐digital rectal examination urine sampling

UroPrecision, EarlyView.
Abstract Background The diagnosis of prostate cancer (PCa) is limited by low specificity and invasiveness. This study aims to establish a highly accurate, noninvasive reverse transcription‐quantitative polymerase chain reaction (RT‐qPCR)‐based urinary prostate cancer antigen 3 (PCA3) assay system and explore the feasibility of using first‐morning urine
Jianglei Xu, Lu Yang, Cong Shi, Yiwei Jiang, Jing Chen, Xiaoxiao Sun, Xuejuan Gao, Xian Wang, Jianzhong Jiang, Xiuzhi Duan, Xuchu Wang, Yiyi Xie, Zhixian Yu, Zhihua Tao, Xiaobing Dou, Chunyu Jin   +15 more
wiley   +1 more source

A Retrospective Cost-Effectiveness Analysis of S-Amlodipine in China [PDF]

Value in Health, 2014
Hu, S.L., Zhang, Y., He, J., Du, L.
openaire   +3 more sources

An Open Label Parallel Group Study to Assess the Effects of Amlodipine and Cilnidipine on Pulse Wave Velocity and Augmentation Pressures in Mild to Moderate Essential Hypertensive Patients [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: Hypertension is a major cardiovascular risk factor, which affects both large and small arteries. Because of the associated morbidity and mortality and the cost to society, it is an important public health challenge.
Rama Mohan Pathapati, Sujith Tumkur Rajashekar, Madhavulu Buchineni, Rajesh Kumar Meriga, Chirra Bhakthavasthala Reddy, Kolla Praveen Kumar   +5 more
doaj   +1 more source

Amlodipine Ameliorates Up-Regulation of ET-1 in Left Ventricle of Hypercholesterolemia Rabbits [PDF]

Iranian Journal of Basic Medical Sciences, 2010
Objective(s)In addition to antihypertensive effects, amlodipine may exhibit cardiovascular protective effects in heart tissue. The aim of this study was to evaluate the effects of amlodipine and/or high cholesterol diet on blood, heart tissue ...
Iraj Salehi, Safar Farajnia, Mustafa Mohammadi, Masoud Sabouri Ghannad   +3 more
doaj  

S-amlodipine improves endothelial dysfunction via the RANK/RANKL/OPG system by regulating microRNA-155 in hypertension

Biomedicine & Pharmacotherapy, 2019
S-amlodipine has been broadly used to treat hypertension, but its protective effects and underlying mechanism remain controversial. The purpose of our study was to investigate the mechanism by which S-amlodipine improves endothelial dysfunction. Specifically, we investigated if S-amlodipine regulates RANK/RANKL/OPG and micro-RNA 155 (miR-155) levels ...
Jining, Yang, Daoyuan, Si, Yanan, Zhao, Chengyan, He, Ping, Yang   +4 more
openaire   +2 more sources

Insights from a six‐year hair drug analysis compendium in drug‐facilitated crimes involving vulnerable population cases

Journal of Forensic Sciences, EarlyView.
Abstract Hair analysis is a well‐established matrix in forensic toxicology, offering a valuable alternative or complement to traditional matrices in diverse contexts, including drug‐facilitated crimes (DFC), elder abuse, and accidental exposure in children.
Amandine Fort, Coralie Boudin, Hélène Eysseric‐Guerin, Virginie Scolan, François Paysant, Cloé Scherpereel, Mélissa Revet, Françoise Stanke‐Labesque, Théo Willeman   +8 more
wiley   +1 more source

The translational potential of experimental pharmacology for cerebrovascular disorders

Анналы клинической и экспериментальной неврологии, 2019
The efficacy of reperfusion therapy to restore cerebral blood supply in patients with ischaemic cerebrovascular disorders is well recognized. Medications with proven cerebrovascular activity, such as oxymethylethylpyridine succinate (Mexidol), nicotinoyl-
Ruben S. Mirzoian, Tamara S. Gan’shina, Galina A. Kim, Elena V. Kurza, Denis V. Maslennikov, Il'ya N. Kurdyumov, Antonina I. Turilova, Aleksander A. Gorbunov   +7 more
doaj   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Renin-Angiotensin System Blockade Associated with Statin Improves Endothelial Function in Diabetics

Arquivos Brasileiros de Cardiologia, 2015
Background:Studies suggest that statins have pleiotropic effects, such as reduction in blood pressure, and improvement in endothelial function and vascular stiffness.Objective:To analyze if prior statin use influences the effect of renin-angiotensin ...
Ronaldo Altenburg Gismondi, Ricardo Bedirian, Cesar Romaro Pozzobon, Márcia Cristina Ladeira, Wille Oigman, Mário Fritsch Neves   +5 more
doaj   +1 more source

Additional file 1: of S-amlodipine plus chlorthalidone vs. S-amlodipine plus telmisartan in hypertensive patients unresponsive to amlodipine monotherapy: study protocol for a randomized controlled trial

, 2018
SPIRIT 2013 checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 124Â kb)
Jo, Sang-Ho, Park, Sung-Ji, Kim, Eung, Soo-Joong Kim, Hyun-Jae Cho, Song, Jong-Min, Jinho Shin, Park, Jin, Joon-Han Shin, Kyoo-Rok Han, Choi, Dong-Ju   +10 more
openaire   +1 more source