Results 101 to 110 of about 16,373,898 (266)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

BOX BOX BOX

open access: yes, 2019
Research Background: BOX BOX BOX revolves around three self-built portable electronic instruments and foregrounds the unique affordances of DIY technologies while suggesting new aesthetic approaches.
Ferguson, John
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Tissue Box

open access: yes, 2010
'Arts and Crafts' decorated tissue box with William Morris-style floral designs. Maker: Kleenex. Date: 1997 - from the The Betty Smithers Design Collection at Staffordshire University.
The Betty Smithers Design Collection at Staffordshire University   +1 more
core  

Temperature Affects Nest Box Occupancy, Nest Success, and Nestling Size in a Southeastern Population of Eastern Bluebirds (Sialia sialis)

open access: yes, 2022
Given the critical role that temperature plays in avian reproductive biology, rising temperatures as a result of global climate change will likely impact reproductive success of many bird populations. Secondary cavity nesting birds, many of which rely on
Horacek, Christopher G.
core  

Box-particle intensity filter [PDF]

open access: yes, 2012
This paper develops a novel approach for multi-target tracking, called box-particle intensity filter (box-iFilter). The approach is able to cope with unknown clutter, false alarms and estimates the unknown number of targets. Furthermore, it is capable of
Gning, Amadou   +11 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Tungsram Radio Valve Box

open access: yes, 2010
Box containing radio valave wrapped in corrugated paper. Inside box lid 'Do not burn this carton save it for your local salvage collection'. Maker: Tungsram. Date: 1940 (circa) - from the The Betty Smithers Design Collection at Staffordshire University.
The Betty Smithers Design Collection at Staffordshire University   +1 more
core  

DEGENERATE S-BOXES

open access: yesRadio Electronics, Computer Science, Control, 2018
Актуальность. S-блоки являются одним из основных преобразований многих шифров, и поиску S-блоков с улучшенными криптографическими показателями уделяется громадное внимание в литературе этого направления. Тем самым полагается, что есть подстановки (S-блоки), которые следует считать плохими, т.е. такие, которые не подходят для построения надежных шифров.
openaire   +3 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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