Results 181 to 190 of about 1,492,479 (262)

Endo-MedSAM: a promptable vision foundation model adaptation for uterus segmentation on pelvic MRI in endometriosis. [PDF]

Front Reprod Health
AlSaad R, Albasha S, Thomas R.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The other giant: functional significance and divergence of Type I MADS-box genes in the evolution of land plants. [PDF]

J Exp Bot
Qiu Y, Köhler C.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

One-Shot Box-Centric Teaching for Persistent Robotic Sorting-and-Filling with Relative Pose Constraints. [PDF]

Sensors (Basel)
Du W, Wu J.
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling. [PDF]

Elife
Zacharia NK, Kuhns S, Boegholm N, Christensen A, Wang J, Petriman NA, Lorentzen A, Fialova JL, Menguy L, Saunier S, Christensen ST, Andersen JS, Bhogaraju S, Lorentzen E.   +13 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Corrigendum to "Opening the Black Box of agency in contraceptive decision-making: A cross-country qualitative study of a complex process" [SSM - Qualitative Research in Health (2025), (8C), 100615]. [PDF]

SSM Qual Res Health
Suchman L, Himes E, Birabwa C, Challa S, Okumu S, Kwena Z, Ndunyu L, Gitome S, Wekesa P, Nyando M, Kamanga M, Jumbe T, Mtalimanja I, Maluwa A, Atuyambe L, Amongin D, Kaudha B, Kayego A, Idiodi I, Okoli C, Tijani A, Jegede A, Nmadu AG, Dimowo S, Vallin J, Phillips B, Sinha E, Malata A, Bukusi E, Waiswa P, Omoluabi E, Holt K.   +31 more
europepmc   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source