Results 121 to 130 of about 4,109,256 (296)
VaccinesBackground: Mozambique introduced the 10-valent pneumococcal conjugate vaccine (PCV10) in 2013 using a three-dose primary series with no booster dose (3p+0) and later switched to the PCV13 using a schedule of two primary doses with one booster (2p+1). We
Aquino Albino Nhantumbo +16 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Persistent activation of transducin by bleached rhodopsin in salamander rods. [PDF]
, 1996 The hydrolysis-resistant GTP analogue GTP-gamma-S was introduced into rods isolated from the retina of the salamander Ambystoma tigrinum to study the origin of the persistent excitation induced by intense bleaching illumination.
Cornwall, MC, Fain, GL, Matthews, HR
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Exploring the soliloquies of Romeo and Juliet: teacher notes (Active Shakespeare: Capturing evidence of learning) [PDF]
, 2010 Part of the 'Active Shakespeare: Capturing evidence of learning' suite of resources. "What is it about Providing active and engaging ways to integrate Shakespeare in the ongoing periodic assessment of pupils’ reading. What is it for?
core
Studi Francesi, 2004 C. E. analyse d’abord rapidement la tradition manuscrite du «Banquet du Faisan», qui comprend: la version contenue dans les Memoires d’Olivier de La Marche, celle de la Chronique de Mathieu d’Escouchy, celles des manuscrits Paris BnF fr. 11594, Paris BnF fr. 5739, Bruxelles BR IV.1103.
openaire +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Authorized Managerialism Under the Federal Rules— and the Extent of Convergence With Civil-Law Judging [PDF]
, 2007 This article, part of a symposium marking the fortieth anniversary of the United States District Court for the Central District of California, first surveys the (very considerable) extent to which changes in the Federal Rules of Civil Procedure over the ...
Rowe, Thomas D., Jr.
core +1 more source
The Five C’s: Bringing a 1980’s Film into the 21st Century Chinese Language Learning Context
L2 Journal, 2011 Film has become an ever more effective medium of instruction in foreign languages, including Chinese. Developing good textbooks to accompany the films is too labor-intensive to keep pace with the growing production of contemporary films, so it is useful ...
Gloria Bien
doaj
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source