Results 131 to 140 of about 4,109,256 (296)

Spartan Daily, April 9, 1962 [PDF]

open access: yes, 1962
Volume 49, Issue 101https://scholarworks.sjsu.edu/spartandaily/4288/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

The Cowl - v.10 - n.15 - Mar 17, 1948 [PDF]

open access: yes, 1948
The Cowl - student newspaper of Providence College. Volume 10, Number 15 - Mar 17, 1948.

core   +1 more source

Reproductive contributions of Taiwan's foreign wives from the top five source countries

open access: yesDemographic Research, 2011
This research studies the reproductive contributions of Taiwan's foreign wives from China, Vietnam, Indonesia, Thailand, and the Philippines, based on applications of the multinomial logit model to the micro data of the 2003 Census of Foreign ...
Kao-Lee Liaw   +2 more
doaj  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Mother’s Handwashing Practices and Health Outcomes of Under-Five Children in Northwest Ethiopia

open access: yesPediatric Health, Medicine and Therapeutics, 2020
Asefa Adimasu Taddese, 1 Baye Dagnew, 2 Henok Dagne, 3 Zewudu Andualem 3 1Department of Epidemiology and Biostatistics, Institute of Public Health, University of Gondar, Gondar, Ethiopia; 2Department of Human Physiology, School of Medicine, University ...
Taddese AA   +3 more
doaj  

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