Results 121 to 130 of about 1,430,925 (278)
Holographic Electroweak Symmetry Breaking from D-branes
, 2007 We observe several interesting phenomena in a technicolor-like model of electroweak symmetry breaking based on the D4-D8-D8bar system of Sakai and Sugimoto.
Christopher D. Carone +5 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Diophantine conditions in global well-posedness for coupled KdV-type systems
Electronic Journal of Differential Equations, 2009 We consider the global well-posedness problem of a one-parameter family of coupled KdV-type systems both in the periodic and non-periodic setting. When the coupling parameter $alpha = 1$, we prove the global well-posedness in $H^s(mathbb{R}) $ for $s >
Tadahiro Oh
doaj
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Strongly Interacting W's and Z's and the Existence of a Heavy Fourth Generation of Fermions
, 1993 By employing the dictum that axiomatic principles are devoid of predictive power, we find that the elastic unitarity constraint, applied to strong W$_L$W$_L$ scattering, does not alter the assumed spectrum of intermediate states. We consider intermediate
Atkinson +23 more
core +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Comments on Mesonic Correlators in the Worldline Formalism
, 2011 We elaborate on how to incorporate mesonic correlators into the worldline formalism. We consider possible applications to QCD-like theories in various dimensions.
Armoni, Adi, Mintakevich, Oded
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Vector discrete problems: parametrization of an optimality principle and conditions of solvability in the class of algorithms involving linear convolution of criteria [PDF]
Computer Science Journal of Moldova, 2001 An n-criteria problem with a finite set of vector valuations is considered. An optimality principle of this problem is given by an integer-valued parameter s, which is varied from 1 to n-1.
V.A. Emelichev, A.V. Pashkevich
doaj
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source