Results 51 to 60 of about 21,903,266 (275)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Optimization Method of Flow Field for Alleviating Clogging of Mist Eliminator in Desulfurization Tower

发电技术
ObjectivesDesulfurization tower mist eliminator is widely used in coal-fired power plants due to its simple structure and good fog removal effect. However, due to the limitation of its own gas-water separation principle, it is prone to scaling up and ...
LIU Zhuo, CHEN Donglin, WANG Shuqi, YANG Yijiang, YAN Youyang, YANG Zhan   +5 more
doaj   +1 more source

Simulation Analysis for Erosion Wear of Ω-shaped Pipe Based on CFD-DEM Coupling

Shiyou jixie, 2022
In order to discuss the influence of sand particles carried in the transportation of natural gas pipeline on the erosion wear of Ω-shaped pipes, the erosion process of gas-solid two-phase flow in Ω-shaped pipes was numerically simulated by using CFD-DEM ...
Zhou Dapeng, Ma Xuedong, Chen Yan
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Optimization Design of a Novel Passive Micromixer Using Response Surface Methodology [PDF]

Iranian Journal of Chemistry & Chemical Engineering
Biochips and microchemical systems utilize micromixers to mix various reactants in microscale environments effectively. The innovative microfluidic device is described. This study aims to enhance the Mixing Index (MI) by changing geometric parameters and
Ke Wang
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

L-shaped multihole-buffering oil-feeding process

Advances in Mechanical Engineering, 2017
An L-shaped multihole-buffering oil-feeding process is proposed, optimized, and experimentally validated to reduce the shock and disturbance to in-tank oil and bottom sediment caused by oil-feeding.
Liqiong Chen, Lingdi Fu, Kun Huang, Hongfang Lu, Zhihao Zhang, Shijuan Wu   +5 more
doaj   +1 more source

Distribution characteristics of two-phase refrigerant in a return junction connecting parallel narrow channels

Nihon Kikai Gakkai ronbunshu, 2016
A flat tube heat exchanger has attracted attention as one of the solutions to improve energy efficiency and reduce the amount of refrigerant in the development of the air conditioning unit for global warming prevention.
Hiroki MURAKAMI, Akira ISHIBASHI, Shigeo HOSOKAWA, Akio TOMIYAMA   +3 more
doaj   +1 more source