Results 41 to 50 of about 21,903,266 (275)
Theoretical and Applied Mechanics Letters, 2022 In this paper, in order to improve the performance of a linear parabolic collector, the thermal effects of using Al2O3-syltherm oil nanofluid with different concentrations and new flange-shaped turbulators are investigated.
Behzad Shaker +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Effect of Inlet Boundary Layer Thickness on the Flow Within an Annular S-Shaped Duct [PDF]
Journal of Turbomachinery, 1998 Experimental and numerical investigations were carried out to gain a better understanding of the flow characteristics within an annular S-shaped duct, including the effect of the inlet boundary layer (IBL) on the flow. A duct with six struts and the same geometry as that used to connect compressor spools on our experimental small two-spool turbofan ...
Toyotaka Sonoda +2 more
openaire +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
S-shaped Inlet Flow Characteristics Test Rig Design and Experimental Research
DEStech Transactions on Materials Science and Engineering, 2017 An inlet flow characteristics test bench was designed for the high offset s-shaped inlet. Parametric design method was used in the design of direct-connect contraction. Numerical simulation results showed export velocity of the designed contraction distributed uniformly, the boundary layer was thin, which had good air contraction effect.
Jia-wei LI +3 more
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Energies, 2021 The pumped-storage power station is an efficient stability regulator of the power grid. However, due to the instability of the pump-turbine in the S-shaped characteristic region, rotational speed fluctuation is easy to occur in the speed no-load ...
Zhiyan Yang +6 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source