Results 101 to 110 of about 19,689,673 (253)

Divergent Evolution and Local Establishment of Multidrug‐Resistant Shigella sonnei in China

MedComm, Volume 7, Issue 1, January 2026.
• Evolutionary history and local establishment of Chinese Shigella sonnei are unclear. • Chinese S. sonnei developed into four clades and ONPG‐negative variants. • The antimicrobial resistance phenotype of Clade I was due to an IncB/O/K/Z plasmid. • Antimicrobial resistance of Clade II was due to IncFII and IncB/O/K/Z plasmids.
Kangkang Liu, Jian Wang, Chaojie Yang, Yehong Yang, Xin Ge, Hongbo Liu, Xinying Du, Ying Xiang, Kaiyuan Min, Qi Wang, Hui Wang, Chao Wang, Huiqun Jia, Mingjuan Yang, Xiaoying Li, Ligui Wang, Yong Sun, Muti Mahe, Jiayong Zhao, Shijun Li, Deshan Yu, Stephen Baker, Jiangfeng Liu, Xuebin Xu, Hongbin Song, Shaofu Qiu, Juntao Yang   +26 more
wiley   +1 more source

Effect of High‐Pressure Processing Operating Parameters on Microbial Inactivation and Bioactive Protein Preservation in Bovine Milk: A Systematic Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT In the U.S., bovine milk is processed using thermal pasteurization to ensure microbial safety. However, this process alters the structure of heat‐sensitive bioactive proteins associated with the functional benefits of raw milk, including antimicrobial, immunomodulatory, and antioxidant proteins.
Rudy Sykora, Caleb Mark, Marie Biondi Ryan, Bishal Barman, Michael Pitino, David C. Dallas   +5 more
wiley   +1 more source

A Novel sRNA in Shigella flexneri That Regulates Tolerance and Virulence Under Hyperosmotic Pressure

Frontiers in Cellular and Infection Microbiology, 2020
Regulation of the environmental stress response and virulence of Shigella flexneri may involve multiple signaling pathways; however, these mechanisms are not well-defined.
Guang Yang, Guang Yang, Boan Li, Leili Jia, Huaiyu Qiu, Mingjuan Yang, Binghua Zhu, Jing Xie, Shaofu Qiu, Peng Li, Hui Ma, Hongbin Song, Ligui Wang   +12 more
doaj   +1 more source

Outer membrane protein A (OmpA) of Shigella flexneri 2a, induces protective immune response in a mouse model. [PDF]

PLoS ONE, 2011
BACKGROUND: In our earlier studies 34 kDa outer membrane protein (OMP) of Shigella flexneri 2a has been identified as an efficient immunostimulant. KEY RESULTS: In the present study MALDI-TOF MS analysis of the purified 34 kDa OMP of Shigella flexneri 2a
Debasis Pore, Nibedita Mahata, Amit Pal, Manoj K Chakrabarti   +3 more
doaj   +1 more source

Characterisation of a Novel Jumbo Lytic Aeromonas dhakensis Bacteriophage P19 and Its Endolysin

Microbial Biotechnology, Volume 19, Issue 1, January 2026.
A jumbo, lytic myovirus phage P19 against multidrug‐resistant (MDR) Aeromonas dhakensis was isolated from river water. P19 demonstrated robust lytic activity, high thermal and pH stability (pH 6–10, up to 60°C), and no genes associated with lysogeny, virulence or antimicrobial resistance. ORF_358 of P19 encodes for T4‐type lysozyme.
Farhat Ansari, Vandan Nagar
wiley   +1 more source

A novel anti-virulence gene revealed by proteomic analysis in Shigella flexneri 2a

Proteome Science, 2010
Background Shigella flexneri is a gram-negative, facultative pathogen that causes the majority of communicable bacterial dysenteries in developing countries. The virulence factors of S.
Ying Tianyi, Liao Xiang, Liu Xiankai, Shang Na, Cao Xiaoyu, Feng Erling, Zhu Li, Zhao Ge, Wang Jie, Chen Huipeng, Wang Hengliang   +10 more
doaj   +1 more source

Population Pharmacokinetic and Pharmacodynamic Prediction for Tebipenem Pivoxil Treatment of Pediatric Shigellosis

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Increasing antimicrobial resistance poses a serious challenge for the treatment of Shigella infections, and there is an urgent need for alternative antibacterial treatments. We conducted a clinical trial to investigate the efficacy of oral tebipenem pivoxil, compared to intravenous ceftriaxone, in Bangladeshi children with shigellosis.
Cindy X. Zhang, Sharika Nuzhat, Md Ridwan Islam, Syed Jayedul Bashar, Subhasish Das, Rukaeya Amin, Firdausi Qadri, Farhana Khanam, Dilruba Ahmed, Patricia B. Pavlinac, Mohammod Jobayer Chisti, Tahmeed Ahmed, Samuel L. M. Arnold   +12 more
wiley   +1 more source

Shigella sonnei O-Antigen Inhibits Internalization, Vacuole Escape, and Inflammasome Activation

mBio, 2019
Two Shigella species, Shigella flexneri and Shigella sonnei, cause approximately 90% of bacterial dysentery worldwide. While S. flexneri is the dominant species in low-income countries, S.
Jayne L. Watson, Julia Sanchez-Garrido, Philippa J. Goddard, Vincenzo Torraca, Serge Mostowy, Avinash R. Shenoy, Abigail Clements   +6 more
doaj   +1 more source

Targets for the MalI repressor at the divergent Escherichia coliK-12malX-malI promoters [PDF]

, 2010
Random mutagenesis has been used to identify the target DNA sites for the MalI repressor at the divergent Escherichia coli K-12 malX-malI promoters. The malX promoter is repressed by MalI binding to a DNA site located from position -24 to position -9 ...
Barnard, Barne, Busby, Chaudhuri, Clausen, El-Robh, Georgina S. Lloyd, Hollands, Jacob, Lloyd, Lodge, Mitchell, Mitchell, Reidl, Reidl, Rita E. Godfrey, Rojo, Stephen J.W. Busby, Swint-Kruse, Valentin-Hansen, Weickert, West, Zdych   +22 more
core   +1 more source

Causal Association Between Gut Microbiota and Sleep Apnoea Identified by Bayesian Weighted Mendelian Randomisation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT This study investigated the potential causal relationship between gut microbiota (GM) and sleep apnoea using Mendelian randomisation (MR) analysis. Summary‐level genome‐wide association (GWAS) data for 473 GM and sleep apnoea were obtained from the IEU Open GWAS database.
Chenguang Zhang, Yicong Wang, Guanghao Yue, Bin Guo   +3 more
wiley   +1 more source