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Shigella flexneri and Shigella sonnei among children under five in Kenya’s urban informal settlement [PDF]

Gut Pathogens
Background Shigella species are a significant global public health threat with the highest burden of Shigella-associated diarrhoea in children under five years of age, particularly in low- and middle-income countries. Given the high burden of shigellosis
Christine Kioko, John M. Maingi, Cecilia Mbae, Phelgona Otieno, Collins Kebenei, Winfred Mbithi, Amos Njuguna, Schola Kamwethya, Diana Imoli, Darius Ideke, Jessicah Jepchirchir, Kelvin Kering, Samuel Kariuki   +12 more
doaj   +2 more sources

Extended spectrum β-lactamase and integron genes among Shigella flexneri and Shigella sonnei isolated from children with diarrhea in shiraz, Southwest Iran [PDF]

BMC Pediatrics
Shigellosis, a bacterial infection marked by dysentery, is typically a self-limiting disease and can be effectively managed with oral rehydration. However, antibiotics may help reduce the severity and duration of Shigellosis despite rising antimicrobial ...
Keyvan Farhadi, Abolfazl Rafati Zomorodi, Mohammadhassan Hassannezhad, Samane Mohebi, Mohammad Motamedifar, Leila Kasraian   +5 more
doaj   +2 more sources

Immunization of Rabbits with a Quadrivalent Shigella Bioconjugate Vaccine Induces Functional Antibodies Reactive with Shigella Isolates from Kenya

mSphere, 2022
Diarrheal diseases are a leading cause of global morbidity and mortality, disproportionately affecting children in resource-limited settings. Although improvements in hygiene and access to clean water are helpful, vaccines are considered essential due to
Elizabeth A. Odundo, Hailey P. Weerts, Lillian Musila, Lilian Ogonda, Anita M. Dreyer, Joerg Schneider, Paula Carranza, Robert W. Kaminski   +7 more
doaj   +1 more source

Bacteroides thetaiotaomicron Outer Membrane Vesicles Modulate Virulence of Shigella flexneri

mBio, 2022
The role of the gut microbiota in the pathogenesis of Shigella flexneri remains largely unknown. To understand the impact of the gut microbiota on S.
Nicholas L. Xerri, Shelley M. Payne
doaj   +1 more source

No Isolate, No Problem: Using a Novel Insertion Sequence PCR to Link Rats to Human Shigellosis Cases in an Underserved Urban Community

Microbiology Spectrum, 2023
During an investigation into a cluster of Shigella flexneri serotype 2a cases in an underserved community, we assessed the relatedness of human and rat S.
Gordon Ritchie, Victor Leung, Chelsea G. Himsworth, Kaylee A. Byers, Lisa K. F. Lee, Samuel D. Chorlton, Aleksandra Stefanovic, Marc G. Romney, Nancy Matic, Christopher F. Lowe   +9 more
doaj   +1 more source

Concordance between Genotypic and Phenotypic Drug-Resistant Profiles of Shigella Isolates from Taiyuan City, Shanxi Province, China, 2005 to 2016

Microbiology Spectrum, 2023
Antimicrobial resistance in Shigella spp. is a global public health concern. In this study, the AMR phenotypic profiles of 10 kinds of antibiotics were compared with the genotypic profiles using genomic analysis of 218 Shigella isolates from Taiyuan City,
Mimi Kong, Chunmei Liu, Yang Xu, Jitao Wang, Dong Jin   +4 more
doaj   +1 more source

12 TEXTILE DYES DECOLORIZATION BY COPPER-RESISTANT-BACTERIA KLEBSIELLA GRIMONTII, SHIGELLA FLEXNERI, ENTEROBACTER CLOACAE ISOLATED FROM CISADANE RIVER TANGERANG

BioLink, 2023
Dyes and copper are dangerous contaminants because they are toxic. Bioremediation using indigenous bacteria is the best solution to overcome water pollution.
Wahyu Irawati, Vania Austine Callista Timotius, Ruben Patrick Adhiwijaya, Bellen Mouretta, Steven Anggawinata, Eunike Bunga Marvella   +5 more
doaj   +1 more source

Formate Promotes Shigella Intercellular Spread and Virulence Gene Expression

mBio, 2018
The intracellular human pathogen Shigella flexneri invades the colon epithelium, replicates to high cell density within the host cell, and then spreads to adjacent epithelial cells. When S.
Benjamin J. Koestler, Carolyn R. Fisher, Shelley M. Payne   +2 more
doaj   +1 more source

Speciation and Antibiotic Susceptibility Pattern of Shigella isolates in a Rural Tertiary Care Hospital, Kolar

Journal of Pure and Applied Microbiology, 2022
Shigellosis is the most important cause of bacillary dysentery. It’s a major public health problem. It is endemic in many developing countries resulting in a significant amount of mortality and morbidity.
Parimala Subramani, Bharathi Ramachandra, Beena Pavangada Madappa, Arvind Natarajan   +3 more
doaj   +1 more source

Cross-Protective Shigella Whole-Cell Vaccine With a Truncated O-Polysaccharide Chain

Frontiers in Microbiology, 2018
Shigella is a highly prevalent bacterium causing acute diarrhea and dysentery in developing countries. Shigella infections are treated with antibiotics but Shigellae are increasingly resistant to these drugs.
Min Jung Kim, Min Jung Kim, Young-hye Moon, Heejoo Kim, Semi Rho, Young Kee Shin, Manki Song, Richard Walker, Cecil Czerkinsky, Cecil Czerkinsky, Dong Wook Kim, Jae-Ouk Kim   +11 more
doaj   +1 more source