Results 21 to 30 of about 22,657 (216)

Host protein phosphorylation during "Shigella flexneri" infection : a phosphoproteomic based systems biology approach [PDF]

open access: yes, 2015
The enteroinvasive bacterium Shigella flexneri triggers its uptake into epithelial cells by injecting several effector proteins via its type three secretion system (TTSS) and interferes with various host cell processes at later stages of infection.
Schmutz, Christoph
core   +1 more source

Rationalizing the design of a broad coverage Shigella vaccine based on evaluation of immunological cross-reactivity among S. flexneri serotypes.

open access: yesPLoS Neglected Tropical Diseases, 2021
No vaccine to protect against an estimated 238,000 shigellosis deaths per year is widely available. S. sonnei is the most prevalent Shigella, and multiple serotypes of S. flexneri, which change regionally and globally, also cause significant disease. The
Francesco Citiulo   +11 more
doaj   +1 more source

12 TEXTILE DYES DECOLORIZATION BY COPPER-RESISTANT-BACTERIA KLEBSIELLA GRIMONTII, SHIGELLA FLEXNERI, ENTEROBACTER CLOACAE ISOLATED FROM CISADANE RIVER TANGERANG

open access: yesBioLink, 2023
Dyes and copper are dangerous contaminants because they are toxic. Bioremediation using indigenous bacteria is the best solution to overcome water pollution.
Wahyu Irawati   +5 more
doaj   +1 more source

Cross-Protective Shigella Whole-Cell Vaccine With a Truncated O-Polysaccharide Chain

open access: yesFrontiers in Microbiology, 2018
Shigella is a highly prevalent bacterium causing acute diarrhea and dysentery in developing countries. Shigella infections are treated with antibiotics but Shigellae are increasingly resistant to these drugs.
Min Jung Kim   +11 more
doaj   +1 more source

Elucidation of a molecular mechanism controlling inflammation during bacterial infection [PDF]

open access: yes, 2015
Recently we described a mechanism of gap junction-mediated communication between infected and uninfected epithelial cells that potentiates innate immunity during infection by the enteroinvasive bacterium Shigella flexneri.
Tschon, Therese
core   +1 more source

Lactoferrin-binding proteins in Shigella flexneri [PDF]

open access: yesInfection and Immunity, 1992
The ability of Shigella flexneri to interact with lactoferrin (Lf) was examined with a 125I-labeled protein-binding assay. The percent binding of human lactoferrin (HLf) and bovine lactoferrin (BLf) to 45 S. flexneri strains was 19 +/- 3 and 21 +/- 3 (mean +/- standard error of the mean), respectively.
Z, Tigyi   +4 more
openaire   +2 more sources

Amplifying the innate immune response : cell-cell propagation of proinflammatory signals during bacterial infection [PDF]

open access: yes, 2012
The enteroinvasive bacterium Shigella flexneri uses multiple secreted effector proteins to downregulate interleukin-8 (IL-8) expression in infected epithelial cells. Nevertheless, massive IL-8 secretion is observed in shigellosis. In this thesis, a novel
Kasper, Christoph Alexander
core   +1 more source

Phylogenetic and Evolutionary Analysis Reveals the Recent Dominance of Ciprofloxacin-Resistant Shigella sonnei and Local Persistence of S. flexneri Clones in India

open access: yesmSphere, 2020
Shigella is the second leading cause of bacterial diarrhea worldwide. Recently, Shigella sonnei seems to be replacing Shigella flexneri in low- and middle-income countries undergoing economic development.
Dhiviya Prabaa Muthuirulandi Sethuvel   +8 more
doaj   +1 more source

Identification of MHC Class II Immunopeptidomes from Shigella flexneri 2a-infected Macrophages as Potential Vaccine Candidates

open access: yesIndonesian Biomedical Journal, 2022
BACKGROUND: Shigella is a Gram-negative rod-shaped intracellular bacterial pathogen that causes bacterial dysentery or shigellosis among children under five years old.
Nor Raihan Mohammad Shabani   +5 more
doaj   +1 more source

In vivo apoptosis in Shigella flexneri infections [PDF]

open access: yesInfection and Immunity, 1996
Shigella flexneri, an etiological agent of bacillary dysentery, causes apoptosis in vitro. Here we show that it also induces apoptosis in vivo. We were able to quantify the number of apoptotic cells in rabbit Peyer's patches infected with S. flexneri by detecting cells with fragmented DNA. Infection with virulent S.
A, Zychlinsky   +5 more
openaire   +2 more sources

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