Results 71 to 80 of about 19,689,673 (253)

Shigella Draft Genome Sequences: Resources for Food Safety and Public Health. [PDF]

open access: yes, 2017
Shigella is a major foodborne pathogen that infects humans and nonhuman primates and is the major cause of dysentery and reactive arthritis worldwide. This is the initial public release of 16 Shigella genome sequences from four species sequenced as part ...
Chen, Poyin   +5 more
core   +1 more source

Shigella flexneri serotype 1c derived from serotype 1a by acquisition of gtrIC gene cluster via a bacteriophage [PDF]

open access: yes, 2016
BACKGROUND: Shigella spp. are the primary causative agents of bacillary dysentery. Since its emergence in the late 1980s, the S. flexneri serotype 1c remains poorly understood, particularly with regard to its
Cam, Phung D   +4 more
core   +1 more source

Vm–MSI: a Vancomycin–Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

open access: yesAdvanced Science, EarlyView.
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li   +7 more
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

Reaksi antigen-antibodi antara protein sub unit pili 18 KDa Shigella flexneri dengan sub unit outer membran protein (OMP) Shigella dysentriae: Strategi memperoleh vaksin shigellosis berbasis protein pili [PDF]

open access: yes, 2016
Bloody diarrhea disease remains a major cause of the high morbidity and mortality of children globally. Diarrhea caused by S. flexneri and S. dysentriae commonly treated with antibiotics seen already started resistant to existing antibiotics varied while
Fitrianingsih, Avin Ainur   +1 more
core  

Bordetella BcrH1 and BcrH2 Are Specific Chaperones for the Pore‐Forming Complex

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT Bordetella has a type III secretion system that secretes virulence proteins crucial to the establishment of infection. The genes encoding components of the Bordetella type III secretion system are located in the bsc region on the chromosome. This region includes the bcrH1 and bcrH2 genes, which respectively encode the proteins BcrH1 and BcrH2.
Yuya Kishino   +4 more
wiley   +1 more source

Saccharomyces boulardii as effective probiotic against Shiegella flexneri in mice

open access: yesمجلة مركز بحوث التقنيات الاحيائية, 2014
This study was designed to evaluate the ability of Saccharomyce buolardi as effective probiotic against Shiegella flexneri. Mice treated with S. boulardii and infected with Sh.
Nedhaal S. Zbar   +2 more
doaj   +1 more source

Shigella-specific antibodies in the first year of life among Zambian infants: A longitudinal cohort study.

open access: yesPLoS ONE, 2021
IntroductionShigellosis, is a leading cause of moderate-to-severe diarrhoea and related mortality in young children in low and middle income countries (LMICs).
Caroline C Chisenga   +11 more
doaj   +1 more source

Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]

open access: yes, 2020
The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
core   +2 more sources

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

open access: yesThe FEBS Journal, EarlyView.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source

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