Results 71 to 80 of about 21,319,883 (205)

Genesis of a novel Shigella flexneri serotype by sequential infection of serotype-converting bacteriophages SfX and SfI

BMC Microbiology, 2011
Background Shigella flexneri is the major pathogen causing bacillary dysentery. Fifteen serotypes have been recognized up to now. The genesis of new S. flexneri serotypes is commonly mediated by serotype-converting bacteriophages.
Sun Qiangzheng, Lan Ruiting, Wang Yiting, Wang Jianping, Luo Xia, Zhang Shaomin, Li Peijing, Wang Yan, Ye Changyun, Jing Huaiqi, Xu Jianguo   +10 more
doaj   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

The evolutionary history of Shigella flexneri serotype 6 in Asia. [PDF]

, 2021
Shigella flexneri serotype 6 is an understudied cause of diarrhoeal diseases in developing countries, and has been proposed as one of the major targets for vaccine development against shigellosis. Despite being named as S.
Turner, Paul, Ha Thanh, Tuyen, Voong Vinh, Phat, Pham, Duy Thanh, Wangchuk, Sonam, Mai, Si-Nguyen T, Thomson, Nicholas R, Rabaa, Maia A, Thwaites, Guy E, Bodhidatta, Ladaporn, Baker, Stephen, Chung The, Hao   +11 more
core   +2 more sources

A new gut pathogenic bacteria and its metabolites promote colorectal cancer development and act as non-invasive early diagnostic biomarkers

Gut Microbes
Gut microbiota dysbiosis is strongly linked to colorectal cancer (CRC), but reliable early diagnostic markers remain elusive. This study investigates the role of a novel Shigella flexneri strain in CRC pathogenesis.
Rui Zhang, Mingxiao Li, Hui Tan, Jianyao Liu, Lu Wang, Wenling Dai, Zhimin Fan, Jihua Liu   +7 more
doaj   +1 more source

Untersuchung von Anti‐Glykan‐Antikörpern und Erforschung ihres medizinischen Potenzials mithilfe synthetischer Glykane

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Anti‐Glykan‐Antikörper spielen sowohl bei Gesundheit als auch bei Krankheit eine wesentliche Rolle. Der Zugang zu neuartigen Glykanstrukturen ermöglicht Fortschritte bei der Antikörpercharakterisierung für die Entdeckung von Biomarkern, die Antikörperentwicklung und das Impfstoffdesign.
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Transcriptional profiling of zebrafish identifies host factors controlling susceptibility to Shigella flexneri [PDF]

Shigella flexneri is a human-adapted pathovar of Escherichia coli that can invade the intestinal epithelium, causing inflammation and bacillary dysentery. Although an important human pathogen, the host response to S. flexneri has not been fully described.
Mazon-Moya, M., Willis, A., Duggan, G., Mostowy, S., Torraca, V., White, R., Sealy, I., Busch-Nentwich, E.   +7 more
core   +1 more source

Species-wide whole genome sequencing reveals historical global spread and recent local persistence in Shigella flexneri

eLife, 2015
Shigella flexneri is the most common cause of bacterial dysentery in low-income countries. Despite this, S. flexneri remains largely unexplored from a genomic standpoint and is still described using a vocabulary based on serotyping reactions developed ...
Thomas R Connor, Clare R Barker, Kate S Baker, François-Xavier Weill, Kaisar Ali Talukder, Anthony M Smith, Stephen Baker, Malika Gouali, Duy Pham Thanh, Ishrat Jahan Azmi, Wanderley Dias da Silveira, Torsten Semmler, Lothar H Wieler, Claire Jenkins, Alejandro Cravioto, Shah M Faruque, Julian Parkhill, Dong Wook Kim, Karen H Keddy, Nicholas R Thomson   +19 more
doaj   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Virulence genes expression profiling of different Shigella flexneri serotypes in response to sub-inhibitory concentrations of azithromycin and ciprofloxacin

Gut Pathogens, 2022
Background Shigellosis is a self-limiting disease that antibiotic therapy could decrease its complications and duration. However, sublethal levels of antibiotics, may lead to alteration in disease state, besides its role in the emergence of resistant ...
Mehrzad Sadredinamin, Mahdi Shabani, Abdollah Karimi, Mohammad-Reza Sohrabi, Mohammadmahdi Karimi-Yazdi, Zohreh Ghalavand, Masoud Alebouyeh   +6 more
doaj   +1 more source

AI‐Assisted SERS in Bacterial Diagnosis and Antimicrobial Susceptibility Testing: Advances, Gaps, and Translational Pathways

Advanced Sensor Research, Volume 5, Issue 9, September 2026.
This review examines recent advances in integrating artificial intelligence (AI) with surface‐enhanced Raman spectroscopy (SERS) for the detection of pathogenic bacteria and evaluation of drug resistance phenotypes. Key challenges in clinical translation are critically discussed, along with prospective solutions and future research directions ...
Chen Liu, Yu Liu, Junlu Wang, Yujie Liu, Qijia Zhan, Jiangang Liu, Ruoping Chen, Kun Zhang   +7 more
wiley   +1 more source