Results 71 to 80 of about 20,475 (213)

A new gut pathogenic bacteria and its metabolites promote colorectal cancer development and act as non-invasive early diagnostic biomarkers

Gut Microbes
Gut microbiota dysbiosis is strongly linked to colorectal cancer (CRC), but reliable early diagnostic markers remain elusive. This study investigates the role of a novel Shigella flexneri strain in CRC pathogenesis.
Rui Zhang, Mingxiao Li, Hui Tan, Jianyao Liu, Lu Wang, Wenling Dai, Zhimin Fan, Jihua Liu   +7 more
doaj   +1 more source

Genesis of a novel Shigella flexneri serotype by sequential infection of serotype-converting bacteriophages SfX and SfI

BMC Microbiology, 2011
Background Shigella flexneri is the major pathogen causing bacillary dysentery. Fifteen serotypes have been recognized up to now. The genesis of new S. flexneri serotypes is commonly mediated by serotype-converting bacteriophages.
Sun Qiangzheng, Lan Ruiting, Wang Yiting, Wang Jianping, Luo Xia, Zhang Shaomin, Li Peijing, Wang Yan, Ye Changyun, Jing Huaiqi, Xu Jianguo   +10 more
doaj   +1 more source

Microbial Safety of Legumes—A Review: Bacterial Contamination, Foodborne Outbreaks, and Traditional and Innovative Mitigation Strategies

Legume Science, Volume 8, Issue 2, June 2026.
ABSTRACT Demand for plant‐based foods, including legumes, is growing as a result of consumer preferences shifting toward food sustainability and plant‐based, protein‐rich foods. However, to ensure the food safety of such alternatives, assessing the prevalence of foodborne pathogens related to these products is critical, especially with their increasing
Natoavina T. Faliarizao, Narindra Randriamiarintsoa, Teresa M. Bergholz, Kirk D. Dolan   +3 more
wiley   +1 more source

Molecular studies of three novel bacteriophages of shigella flexneri [PDF]

, 2018
Temperate bacteriophages play a crucial role in the pathogenesis of Shigella flexneri. They modify the O-antigen of the host, leading to increased virulence and immune evasion. Characterization of S.
Jakhetia, Richa
core   +1 more source

Species-wide whole genome sequencing reveals historical global spread and recent local persistence in Shigella flexneri

eLife, 2015
Shigella flexneri is the most common cause of bacterial dysentery in low-income countries. Despite this, S. flexneri remains largely unexplored from a genomic standpoint and is still described using a vocabulary based on serotyping reactions developed ...
Thomas R Connor, Clare R Barker, Kate S Baker, François-Xavier Weill, Kaisar Ali Talukder, Anthony M Smith, Stephen Baker, Malika Gouali, Duy Pham Thanh, Ishrat Jahan Azmi, Wanderley Dias da Silveira, Torsten Semmler, Lothar H Wieler, Claire Jenkins, Alejandro Cravioto, Shah M Faruque, Julian Parkhill, Dong Wook Kim, Karen H Keddy, Nicholas R Thomson   +19 more
doaj   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

MedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang, Jingfei Shi, Linlin Xu, Guangrui Zhao, Yue Chen, Lin Cheng, Xiaokang Li, Zhigang Sun, Shuhong Huang   +8 more
wiley   +1 more source

Effects of knockdown of S. flexneri-induced host response genes on nematode survival.

, 2014
After RNAi knockdown of S. flexneri-induced genes aco-1 (B), cct-2 (C), daf-19 (D) and hsp-60 (E), young adult hermaphrodites were transferred onto lawns of either E. coli OP50, avirulent S. flexneri (SFL1223) or virulent S. flexneri serotype 3b (SFL1520)
David H. Hall (230862), Carolyn A. Behm (198623), Naresh K. Verma (555317), Ulrike Mathesius (41952), Melanie Rug (625764), Divya T. George (555316), Ken C. Q. Nguyen (249690)   +6 more
core   +1 more source

Virulence genes expression profiling of different Shigella flexneri serotypes in response to sub-inhibitory concentrations of azithromycin and ciprofloxacin

Gut Pathogens, 2022
Background Shigellosis is a self-limiting disease that antibiotic therapy could decrease its complications and duration. However, sublethal levels of antibiotics, may lead to alteration in disease state, besides its role in the emergence of resistant ...
Mehrzad Sadredinamin, Mahdi Shabani, Abdollah Karimi, Mohammad-Reza Sohrabi, Mohammadmahdi Karimi-Yazdi, Zohreh Ghalavand, Masoud Alebouyeh   +6 more
doaj   +1 more source

Septins in the Middle—Makers and Breakers of Membrane Contact Sites

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Septins are a family of GTP‐binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. Growing evidence places septins at membrane contact sites (MCS) — key hubs for intracellular communication that mediate exchange of ions, lipids, and ...
TrishaJean J. Holt, Elias T. Spiliotis
wiley   +1 more source

Fermented Foods and Beverages of Ethiopia: Substrates, Traditional Preparation Techniques, and Nutritional Quality

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Traditional Ethiopian fermented foods and beverages such as Injera, Kocho, and Tella provide important health benefits, including improved nutrient bioavailability, gut health, and digestibility. However, challenges such as lack of standardization, insufficient documentation, and economic constraints limit their wider development and commercialization.
Limenew Abate Worku, Rakesh Kumar Bachheti, Vikas Rana, Gyanesh Joshi, Archana Bachheti, D. P. Pandey   +5 more
wiley   +1 more source