Evidence of maternal transfer of antigen-specific antibodies in serum and breast milk to infants at high-risk of S. pneumoniae and H. influenzae disease. [PDF]
Front Immunol, 2022 Martinovich KM +8 more
europepmc +1 more source
Interdisciplinary Medicine, EarlyView.TargetGen‐recurrent neural network (RNN), an advanced generative model, generated 28,708 unique and novel compounds, identifying SAK‐2970 as a potent antibiotic against drug‐resistant Staphylococcus aureus. Exhibiting strong biofilm inhibition, high therapeutic efficacy, and minimal systemic toxicity in vivo, SAK‐2970 highlights its safety and clinical
Shakeel Ahmad Khan +2 more
wiley +1 more source
USE OF A MODIFIED FLUORESCENT IN SITU HYBRIDIZATION PROCEDURE TO IMPROVE THE IDENTIFICATION OF STREPTOCOCCUS PNEUMONIAE IN BLOOD CULTURES [PDF]
, 2013 Streptococcus pneumoniae is an important causative agent for bacteremia. Fluorescent in situ hybridization (FISH) is a helpful molecular technique for the rapid identification of S. pneumoniae in positive blood cultures.
GHARIBI, SOMAYYEH +3 more
core
Frontiers in the Management of Orthopaedic Periprosthetic Joint Infection
Journal of Orthopaedic Research, EarlyView.ABSTRACT Periprosthetic joint infection (PJI) is a devastating complication of total joint arthroplasty (TJA), one of the most frequently performed surgical procedures worldwide. Management of acute PJI commonly involves debridement, antibiotics, and implant retention (DAIR), though failure rates remain high due to antibiotic‐tolerant biofilms. Chronic
Michael F. Shannon +9 more
wiley +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2015 Aim. Study protective activity of protein-containing antigens of pneumococcus, obtained from serotypes 6В, 10А, 14, 19F, 23F and 36R, against infection with heterologous strains of S. pneumoniae. Materials and methods. S.
D. S Vorobiev +5 more
doaj
Scientific ReportsStreptococcus pneumoniae is a significant pathogen causing infectious diseases, including pneumonia, otitis media, septicemia, and meningitis. The introduction of multivalent vaccines has coincided with a remarkable decrease in the number of pneumococcal-
Yun Xing +5 more
doaj +1 more source
Dynamic Python-Based Method Provides Quantitative Analysis of Intercellular Junction Organization During S. pneumoniae Infection of the Respiratory Epithelium. [PDF]
Front Cell Infect Microbiol, 2022 Mo D, Xu S, Rosa JP, Hasan S, Adams W.
europepmc +1 more source
Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease
Journal of Periodontology, EarlyView.Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar +11 more
wiley +1 more source
Liposomal Encapsulation of Polysaccharides (LEPS) as an Effective Vaccine Strategy to Protect Aged Hosts Against S. pneumoniae Infection. [PDF]
Front Aging, 2021 Bhalla M +7 more
europepmc +1 more source
JPGN Reports, EarlyView.Abstract Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening hyperinflammatory syndrome that can occur after solid organ transplantation but remains underrecognized in this setting. The diagnosis is often delayed due to overlapping clinical manifestations with infection, rejection, or malignancy, and management becomes particularly ...
Chen Chen +6 more
wiley +1 more source