Results 21 to 30 of about 22,695,467 (240)
Superantigenic Activity of emm3 Streptococcus pyogenes Is Abrogated by a Conserved, Naturally Occurring smeZ Mutation [PDF]
, 2012 Streptococcus pyogenes M/emm3 strains have been epidemiologically linked with enhanced infection severity and risk of streptococcal toxic shock syndrome (STSS), a syndrome triggered by superantigenic stimulation of T cells. Comparison of S.McGregor, Karen, Davies, F.J., Frances J Davies, Chong, Deborah L. W., McGregor, K., Davies, Frances J., McGregor, K, Leili Farzaneh, Spratt, BG, Leili Farzaneh (130255), Pichon, B., Shiranee Sriskandan, Efstratiou, A, McGregor Karen, Bruno Pichon (130249), Pichon, B, Holden, Matthew T. G., Davies, FJ, Mary Sommerlad, Androulla Efstratiou, Turner, CE, Sommerlad, M, Chong, DLW, Sriskandan Shiranee, Mary Sommerlad (130242), Sommerlad, M., Turner Claire E., Farzaneh, L., Brian G Spratt, Deborah L. W. Chong (130252), Brian G. Spratt (10001), Sriskandan, Shiranee, Holden, M.T., Holden, MTG, Matthew T G Holden, Sriskandan, S., Androulla Efstratiou (130260), Sommerlad Mary, Matthew T. G. Holden (130258), Pichon Bruno, Frances J. Davies (130247), Spratt, B.G., Shiranee Sriskandan (16154), Holden Matthew T. G., Karen McGregor (130245), Chong Deborah L. W., Turner, C.E., Karen McGregor, Sommerlad, Mary, Farzaneh, L, Sriskandan, S, Claire E Turner, Davies Frances J., Pichon, Bruno, Efstratiou, A., Farzaneh, Leili, Spratt Brian G., Claire E. Turner (130239), Spratt, Brian G., Efstratiou, Androulla, Efstratiou Androulla, Chong, D.L., Deborah L W Chong, Bruno Pichon, Farzaneh Leili, Turner, Claire E., Holden, Matthew T. G.; id_orcid +66 morecore +1 more sourceMolecular analysis of an outbreak of lethal postpartum sepsis caused by Streptococcus pyogenes [PDF]
, 2013 This work was supported by the United Kingdom Clinical Research Collaboration, which funds the National Centre for Infection Prevention and Management at Imperial College London.Holden, M.T., Bentley, S.D., Holden, MTG, Davies, F.J., Sriskandan, S., Dryden, M., Davies, Frances J., Bentley, SD, Lawrenson, RA, Turner, C.E., Farzaneh, L, Sriskandan, S, Efstratiou, A, Holden, Matthew Thomas Geoffrey, Bentley, Stephen D., Dryden, M, Davies, FJ, Efstratiou, A., Farzaneh, Leili, Turner, CE, Lawrenson, Richard A., Efstratiou, Androulla, Lawrenson, R.A., Farzaneh, L., Turner, Claire E., Sriskandan, Shiranee, Dryden, Matthew, Holden, Matthew Thomas Geoffrey; id_orcid +27 morecore +1 more sourceGenomic evidence for the evolution of Streptococcus equi : host restriction, increased virulence, and genetic exchange with human pathogens [PDF]
, 2009 The continued evolution of bacterial pathogens has major implications for both human and animal disease, but the exchange of genetic material between host-restricted pathogens is rarely considered. Streptococcus equi subspecies equi (S.Parkhill Julian, Maskell, Duncan, Kehoe Michael, Robinson, Carl, Spratt, BG, Bason, Nathalie C., Aanensen, David M., Simmonds, M, Aanensen David M., Romain Paillot, Jourdan Thibaud, Willey, David, Maskell Duncan J., Aanensen, David, Katy Webb, Nathalie C Bason, Nancy E Holroyd, Ainslie, F, Maskell, DJ, Robinson Carl, Holden, Matthew, Simmonds Mark, Paillot Romain, Steward, KF, Jourdan, Thibaud, David M Aanensen, Bentley Stephen D., Jolley Keith A., Neil Chanter, Quail, Michael A., Stephen D Bentley, Webb, Katy, Maiden Martin C. J., Julian Parkhill, Brooks Karen, Spratt Brian G., Maiden, MCJ, Fern Ainslie, Mark Simmonds, Keith A Jolley, Spratt, Brian, Holroyd, NE, Parkhill, Julian, Heather Zoe, Chanter, N, Michael Kehoe, Jolley, KA, David Willey, Bentley, Stephen, Ainslie, Fern, Quail, MA, Waller, Andrew S., Sanders Mandy, Waller, AS, Heather, Zoe, Waller, Andrew, Parkhill, J, Bason, NC, Sanders, M, Carl Robinson, Bason Nathalie C., Steward, Karen, Brooks, Karen, Bentley, Stephen D., Paillot, R, Wessels, Michael, Maiden, Martin, Holden, Matthew T. G., Zoe Heather, Robinson, C, Mungall Karen, Steward, Karen F., Quail Michael A., Paillot, Romain, Sanders, Mandy, Quail, Michael, Bason, Nathalie, Holroyd, Nancy, Maiden, Martin C. J., Andrew S Waller, Jolley, Keith A., Willey, D, Brian G Spratt, Chanter Neil, Mungall, K, Webb, K, Holden, MTG, Matthew T G Holden, Holroyd Nancy E., Kehoe, M, Karen F Steward, Maskell, Duncan J., Heather, Z, Holden Matthew T. G., Bentley, SD, Duncan J Maskell, Chanter, Neil, Aanensen, DM, Karen Brooks, Thibaud Jourdan, Brooks, K, Ainslie Fern, Steward Karen F., Holroyd, Nancy E., Mandy Sanders, Michael A Quail, Spratt, Brian G., Willey David, Simmonds, Mark, Waller Andrew S., Mungall, Karen, Webb Katy, Karen Mungall, Jourdan, T, Kehoe, Michael, Martin C J Maiden, Jolley, Keith, Holden, Matthew T. G.; id_orcid +117 morecore +1 more sourceExpt1_CDM_Streptococcus pyogenes
, 2023 Expt. 1: Proteomic comparison of two different lineages of S. pyogenes (5 strains per group). Different fractions of Strep pyogenes (cytosol, cell wall, supernatant) have been compared after culture in chemically defined medium (CDM).(3 files)
Expt 2 ...Shiranee Sriskandan (14299349)core +1 more sourceFragments of bacterial endoglycosidase S and immunoglobulin G reveal subdomains of each that contribute to deglycosylation [PDF]
, 2014 Endoglycosidase S (EndoS) is a glycoside-hydrolase secreted by the bacterium Streptococcus pyogenes. EndoS preferentially hydrolyzes the N-linked glycans from the Fc region of IgG during infection. This hydrolysis impedes Fc functionality and contributes Yu, Xiaojie, Crispin, Max, Vesiljevic, Snezana, Pritchard, Laura K., Mattick, Susan, Scanlan, Christopher N., Baruah, Kavitha, Schnell, Jason R., Higgins, Matthew K., Krishna, Benjamin, Harvey, David J., Dixon, Emma V., Claridge, Jolyon K., Zitzmann, Nicole +13 morecore +1 more sourceInnate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2.
PLoS ONE, 2015 Innate immune recognition of the major human-specific Gram-positive pathogen Streptococcus pyogenes is not understood. Here we show that mice employ Toll-like receptor (TLR) 2- and TLR13-mediated recognition of S. pyogenes.Christina Fieber, Marton Janos, Tina Koestler, Nina Gratz, Xiao-Dong Li, Virginia Castiglia, Marion Aberle, Martina Sauert, Mareike Wegner, Lena Alexopoulou, Carsten J Kirschning, Zhijian J Chen, Arndt von Haeseler, Pavel Kovarik +13 moredoaj +1 more sourceThe Non-phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase GapN Is a Potential New Drug Target in Streptococcus pyogenes
Frontiers in Microbiology, 2022 The strict human pathogen Streptococcus pyogenes causes infections of varying severity, ranging from self-limiting suppurative infections to life-threatening diseases like necrotizing fasciitis or streptococcal toxic shock syndrome.Philip Eisenberg, Leon Albert, Jonathan Teuffel, Eric Zitzow, Claudia Michaelis, Jane Jarick, Clemens Sehlke, Lisa Große, Nicole Bader, Ariane Nunes-Alves, Ariane Nunes-Alves, Bernd Kreikemeyer, Hermann Schindelin, Rebecca C. Wade, Rebecca C. Wade, Rebecca C. Wade, Tomas Fiedler +16 moredoaj +1 more source
