Results 31 to 40 of about 47,037 (210)

Purification and characterization of a peptide essential for formation of streptolysin S by Streptococcus pyogenes [PDF]

Infection and Immunity, 1992
Peptides in a pronase digest of bovine serum albumin were required for streptolysin S formation by Streptococcus pyogenes besides maltose and a carrier (the oligonucleotide fraction obtained by treatment of Saccharomyces cerevisiae RNA with RNase A). A peptide essential for streptolysin S formation was purified to homogeneity from a pronase digest of ...
T, Akao, T, Takahashi, K, Kobashi
openaire   +2 more sources

Conserved and specific features of Streptococcus pyogenes and Streptococcus agalactiae transcriptional landscapes

BMC Genomics, 2019
Background The human pathogen Streptococcus pyogenes, or group A Streptococcus, is responsible for mild infections to life-threatening diseases. To facilitate the characterization of regulatory networks involved in the adaptation of this pathogen to its ...
Isabelle Rosinski-Chupin, Elisabeth Sauvage, Agnès Fouet, Claire Poyart, Philippe Glaser   +4 more
doaj   +1 more source

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A

Angewandte Chemie, EarlyView.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham, Edward S. Hems, Daniel C. L. Van, Justin E. Clarke, Sergey Nepogodiev, Julius S. P. Adamson, Christian Bassi, Michael E. Webb, Glyn R. Hemsworth, Orde Q. Munro, Barrie Wilkinson, Ryan F. Seipke   +11 more
wiley   +2 more sources

S. pyogenes Infections and Its Sequelae

, 2011
L. Guilherme1,3, S. Freschi de Barros1,3 A.C. Tanaka1, M.C. Ribeiro Castro4 and J. Kalil1,2,3 1Heart Institute (InCor), School of Medicine, University of Sao Paulo, Sao Paulo, 2Clinical Immunology and Allergy Division, School of Medicine, University of Sao Paulo, Sao Paulo, 3Immunology Investigation Institute, National Institute for Science and ...
L. Guilherme, S. Freschi de Barros A.C. Tanaka, M.C. Ribeiro, J. Kalil   +3 more
openaire   +2 more sources

A specific and ultrasensitive Cas12a/crRNA assay with recombinase polymerase amplification and lateral flow biosensor technology for the rapid detection of Streptococcus pyogenes

Microbiology Spectrum
The potential of CRISPR/Cas systems for nucleic acid detection in novel biosensing applications is remarkable. The current clinical diagnostic detection of Streptococcus pyogenes (S. pyogenes) is based on serological identification, culture, and PCR.
Yu Cheng, Jiawen Lyu, Jiangfeng Han, Long Feng, Xiangmei Li, Pei Li, Shanfeng Zhang, Wenqiao Zang   +7 more
doaj   +1 more source

A ROLE OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES M49-16 IN PROMOTING INFECTION AND INHIBITION OF ENDOTHELIAL CELL PROLIFERATION

Медицинская иммунология, 2016
Arginine deiminase is a bacterial enzyme that hydrolyses arginine with citrulline and ammonia formation. In recent years, increasing evidence is reported about in vitro and in vivo anti-angiogenic action of arginine deiminase from Mycoplasma spp.
E. A. Starikova, A. B. Karaseva, L. A. Burova, A. N. Suvorov, A. V. Sokolov, V. B. Vasilyev, I. S. Freidlin   +6 more
doaj   +1 more source

EFFECT OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES ON CYTOSKELETON STRUCTURE AND MIGRATION ACTIVITY OF HUMAN ENDOTHELIAL CELLS

Медицинская иммунология, 2017
There is a growing body of data about the cytopathic effect of bacterial arginine deiminase on human endothelial cells, but the precise mechanisms of endothelial dysfunction caused by the activity of the enzyme remain poorly understood.
E. A. Starikova, J. T. Mammedova, L. A. Burova, A. V. Sokolov, V. B. Vasilyev, I. S. Freidlin   +5 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Streptococcus pyogenes-purpura fulminans as an invasive form of group A streptococcal infection

Annals of Clinical Microbiology and Antimicrobials, 2018
Background Streptococcus pyogenes is an uncommon pathogen of purpura fulminans, and the pathogenesis of S. pyogenes-purpura fulminans remains unclear because of paucity of cases. We reported a pediatric case of S.
Sayaka Okuzono, Masataka Ishimura, Shunsuke Kanno, Motoshi Sonoda, Noriyuki Kaku, Yoshitomo Motomura, Hisanori Nishio, Utako Oba, Masuo Hanada, Jun-ichi Fukushi, Michiyo Urata, Dongchon Kang, Hidetoshi Takada, Shouichi Ohga   +13 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source