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Tissue distribution of rat S100 alpha and S100 beta and S100-binding proteins

American Journal of Physiology-Cell Physiology, 1987
To understand the physiological role of the calcium-binding proteins S100 alpha and S100 beta, it is necessary to determine the distribution of these proteins and detect their intracellular targets in various tissues. The distribution of immunoreactive S100 alpha and S100 beta in various rat tissues was examined by radioimmunoassay.
D B, Zimmer, L J, Van Eldik
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Functions of S100 Proteins

Current Molecular Medicine, 2012
The S100 protein family consists of 24 members functionally distributed into three main subgroups: those that only exert intracellular regulatory effects, those with intracellular and extracellular functions and those which mainly exert extracellular regulatory effects.
DONATO, Rosario Francesco   +6 more
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S100 proteins in atherosclerosis

Clinica Chimica Acta, 2020
Atherosclerosis is an arterial disease associated with dyslipidemia, abnormal arterial calcification and oxidative stress. It has been shown that a continued chronic inflammatory state of the arterial wall contributes to the development of atherosclerosis.
Xuan Xiao   +7 more
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The S100 protein family

Trends in Biochemical Sciences, 1988
Abstract The S100 proteins are a group of small Ca 2+ -binding modulator proteins involved in cell cycle progression, cell differentiation, and cytoskeletal-membrane interactions. Recently, many new members of the S100 protein family have been described.
D, Kligman, D C, Hilt
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S100 proteins

1996
Abstract Members of the 5100 Ca2•-binding protein family are typically small, acidic proteins containing two Ca2•-binding sites. It has been suggested, that they are associated with cell cycle progression, differentiation, metabolism, and the generation of neoplastic cells.
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S100 protein in breast tumor

Indian Journal of Cancer, 2014
S100 protein is the largest subtribe in calcium binding protein family. According to recent researches, abnormal expression of S100 protein is often related to tumor, including breast tumor. Breast tumor is the most common malignant disease in female with high mortality mainly due to metastasis.
F, Li, X, Men, W, Zhang
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S100 Calgranulins in inflammatory arthritis

Immunology & Cell Biology, 2009
Calgranulins comprise three proteins, S100A8 (Calgranulin A), S100A9 (Calgranulin B) and S100A12 (Calgranulin C) that are predominantly expressed by neutrophils, monocytes and activated macrophages. These S100 calcium‐binding proteins are important molecular mediators in a range of diseases, including inflammatory arthritis, atherosclerosis and ...
Chandima, Perera   +2 more
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