Results 51 to 60 of about 613,651 (294)

Characterization of multiresistance gene cfr(C) variants in Campylobacter from China.

Journal of Antimicrobial Chemotherapy, 2019
OBJECTIVES To investigate the occurrence, the genetic environment and the functionality of novel variants of the MDR gene cfr(C) in Campylobacter from China.
Dejun Liu, Xing-Hua Li, Weiwen Liu, Hong Yao, Zhihai Liu, A. Feßler, Junjia He, Yuqing Zhou, Zhangqi Shen, Zuowei Wu, S. Schwarz, Qijing Zhang, Yang Wang   +12 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Emergence of blaKPC-2-carrying megaplasmid in carbapenem-resistant Pseudomonas aeruginosa ST1076: Genomic and functional insights

Journal of Global Antimicrobial Resistance
Objective: Carbapenem-resistant Pseudomonas aeruginosa (CRPA) poses a critical challenge to clinical treatment due to its multidrug resistance and genomic plasticity. Here, we report the genomic and functional characterization of an ST1076 P.
Jing Chen, Weidong Zhu, Chen Lin, Zhen Li, Haowei Ye, Danfeng Lou   +5 more
doaj   +1 more source

cagA and vacA in strains of Helicobacter pylori from ulcer and non-ulcerative dyspepsia patients

BMC Gastroenterology, 2002
Background The cytotoxin associated gene A (cagA), and the vacuolating cytotoxin gene A (vacA) of Helicobacter pylori have been associated to phenotypic characteristics of virulence. The objectives of this study were to detect the presence of cagA and to
Figueroa Guillermo, Troncoso Miriam, Faundez Gustavo   +2 more
doaj   +1 more source

Capture Sequencing to Explore and Map Rare Casein Variants in Goats

Frontiers in Genetics, 2021
Genetic variations in the four casein genes CSN1S1, CSN2, CSN1S2, and CSN3 have obtained substantial attention since they affect the milk protein yield, milk composition, cheese processing properties, and digestibility as well as tolerance in human ...
Siham A. Rahmatalla, Siham A. Rahmatalla, Danny Arends, Ammar Said Ahmed, Lubna M. A. Hassan, Stefan Krebs, Monika Reissmann, Gudrun A. Brockmann   +7 more
doaj   +1 more source

Additional file 1: Table S1. of Characterization of wheat MYB genes responsive to high temperatures

, 2017
Primer sequences used in this study (DOCX 24 kb)
Zhao, Yue, Xuejun Tian, Wang, Fei, Liyuan Zhang, Mingming Xin, Zhaorong Hu, Yingyin Yao, Zhongfu Ni, Qixin Sun, Huiru Peng   +9 more
openaire   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

S1 gene sequence analysis of infectious bronchitis virus vaccinal strains (H120 & H52) and their embryo-passaged derivatives

Archives of Razi Institute, 2016
Avian infectious bronchitis is an acute and highly contagious disease that mainly causes respiratory symptoms in poultry. A number of serotypes and variants of the viral agent with poor cross-protection are the major problem to achieve desired immunity ...
Bakhshesh, M., Masoudi, S., Esmaelizad, M., Khalesi, B.   +3 more
doaj  

Alleles controlling apple skin colour and incompatibility in new Czech apple varieties with different degrees of resistance against Venturia inaequalis CKE.

Plant, Soil and Environment, 2005
The skin colour of 21 varieties was assessed on a molecular level. Four varieties had yellow skin colour with the genotype constitution a1a1, a1a2 or a2a2. Seventeen varieties had dominant red colour.
M. Melounová, P. Vejl, P. Sedlák, J. Blažek, J. Zoufalá, Z. Milec, H. Blažková   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source