Results 41 to 50 of about 25,225,437 (145)
Advanced Science, EarlyView.Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi +7 more
wiley +1 more source
Advanced Science, EarlyView.Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang +6 more
wiley +1 more source
Advanced Science, EarlyView.Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Haobo Ge +13 more
wiley +1 more source
Benvinguda a Sant Mateu de Bages (568 m.)
, 1979 BoExcursió del 27 al 28 d'octubre de 1979. Itinerari: Creu Pallarès - La Botiga - Castelltallat (896 m.) - Sant Mateu de Lages (568 m.) - Molí de Borxeda - 'Les Torres' i Sant Vicenç de Fals (480 m.) - Creu del Castell - Senyús ...
José Guiu, Camil, 1937-1991
core
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation
Advanced Science, EarlyView.Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu +10 more
wiley +1 more source
Real‐Time Monitoring of Mass and Mechanical Properties in Single Cells and Multicellular Spheroids
Advanced Science, EarlyView.This study introduces photothermally actuated microcantilevers combined with optical microscopy to simultaneously measure morphology, mass, and mechanical properties of cellular systems in real‐time. The findings link cytoplasm‐dominated mechanical energy dissipation to the Q‐factor as a novel biophysical parameter.
Ilaria Incaviglia +8 more
wiley +1 more source
Effects of R-568 or S-568 +/- Calhex (10 µM) on HUVECs NO production.
, 2013 NO levels (mean value ± SE) in DAF-2DA-loaded HUVEC populations treated with R-568 or S-568 (1–100 µM) +/- Calhex 10 µM (A). eNOS-ser1177 phosphorylation in HUVECs stimulated with R-568 (B) or S-568 (C) (0.1–100 µM) +/- Calhex (10 µM).
Natalia Di Pietro (292164) +10 more
core +1 more source
American Journal of Industrial Medicine, EarlyView.ABSTRACT Background Long COVID affects a significant proportion of COVID‐19 survivors. This study examined persistent Long COVID symptoms among healthcare personnel (HCP) and evaluated associations with vaccination, prior SARS‐CoV‐2 infection, underlying health conditions, and demographics.
Eric Kontowicz +13 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective To develop, externally validate, and simplify a machine learning model to predict remission between 6 and 24 months in patients with rheumatoid arthritis (RA) initiating tumor necrosis factor inhibitors, JAK inhibitors, interleukin‐6 inhibitors, abatacept, or rituximab using data from 11 international registries in the JAK‐pot collaboration ...
Zubeyir Salis +22 more
wiley +1 more source