Results 51 to 60 of about 7,143 (177)

Fluorene‐based blue emitters: On the path to electrically pumped organic lasers

FlexMat, EarlyView.
Electrically pumped efficient operation remains unrealized, a major challenge in optoelectronics. Fluorene‐based blue‐emitting semiconductors are promising gain media, thanks to their structural tunability and favorable emission properties. This review summarizes recent advances, highlights their reliability and versatility in lasing, and outlines key ...
Yong Yan, Hao Li, Mengna Yu, Huiyin Wang, Jiangqiang He, Menghan Wu, Quanyou Feng, Linghai Xie   +7 more
wiley   +1 more source

Counter‐ion modulation: A facile approach toward quenching‐resistant multi‐resonance emitters for efficient narrowband electroluminescence

FlexMat, EarlyView.
Quenching‐resistant carbocation‐based multi‐resonance emitters are developed via a facile counter‐ion modulation strategy, giving much narrowed emission bands under high doping concentrations, and greatly improved device efficiency for solution‐processed narrowband OLEDs by simply increasing the size of counter ions.
Tao Li, Guimin Zhao, Yuanyuan Li, Zhihua Ma, Zhicai Chen, Fangfang Huang, Ronghao Yang, Wei Jiang, Xin Ai, Shiyang Shao   +9 more
wiley   +1 more source

AKT, ATR, and Notch Inhibitors Radiosensitize a Preclinical Model of Adenoid Cystic Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Adenoid Cystic Carcinoma (ACC) is a rare and lethal type of head and neck cancer. Standard therapy involves surgery followed by radiation therapy. The majority of ACC has MYB overexpression and MYB‐NFIB gene fusions, while Notch mutations are associated with aggressive behavior.
Shivani Thoidingjam, Sushmitha Sriramulu, Asya Haider Muratoglu, Stephen Brown, Oudai Hassan, Benjamin Movsas, Haythem Ali, Steven Chang, Patrick Ha, Farzan Siddiqui, Shyam Nyati   +10 more
wiley   +1 more source

Nitrogen‐Based Bisphosphonate Use and Risk of Cancer in Women Aged 50 Years and Older: A National Data Linkage Study

International Journal of Cancer, EarlyView.
Bisphosphonates are widely used to treat osteoporosis and to manage bone metastases in patients with breast cancer. Nitrogen‐based bisphosphonates may also broadly reduce cancer risk, but evidence remains inconsistent. This large population‐based data linkage study in women aged > 50 years found that, compared to no use of osteoporosis medicines ...
Karen M. Tuesley, Fiona Caristo, Katrina Spilsbury, Sallie‐Anne Pearson, Peter Donovan, Michael D. Coory, Christopher B. Steer, Susan J. Jordan   +7 more
wiley   +1 more source

Variant‐Specific Landscape of Mutual Exclusivity Among BRAF, EGFR, and KRAS Oncogenes Reveals Overlap With Functionally Antagonistic Mutant Pairs

International Journal of Cancer, EarlyView.
Mutual exclusivity and co‐occurrence of oncogenic mutations reflect functional antagonism or dependence and may inform therapeutic strategies. However, most studies overlook variant‐level patterns. In this comprehensive, cross‐cohort analysis of BRAF, KRAS, and EGFR mutation subtypes, the most significant mutual exclusivity pairs overlapped with ...
Freya Vaeyens, Jan‐Patrick Hetzel, Khaldoon Abdullah, Carolien Eggermont, Catharina Olsen, Marco Mernberger, Ken Maes, Jelle Vlaeminck, Rainer Claus, Dries Vanisterbecq, Frederik Hes, Martin Pichler, Philippe Giron, Oleg Timofeev, Maxim Noeparast   +14 more
wiley   +1 more source

Longitudinal Associations Between Inflammation and Multi‐Dimensional Fatigue up to 2 Years After Colorectal Cancer Diagnosis

International Journal of Cancer, EarlyView.
Cancer‐related fatigue (CRF) is a common and debilitating symptom among colorectal cancer (CRC) patients, but its underlying biological causes remain unclear, with inflammation emerging as a leading suspect. Here, researchers analyzed inflammatory biomarkers in blood samples and evaluated responses in fatigue assessments from CRC patients at and up to ...
Anouk E. C. Bruijnzeels, Floortje Mols, Katrijn Van Deun, Dounya Schoormans   +3 more
wiley   +1 more source

Second‐trimester multimetabolite panel for early preeclampsia rule‐out

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective We aimed to establish a high‐sensitivity, multimetabolite rule‐out model for the development of preeclampsia (PE), prioritizing minimizing false negatives to exclude low‐risk individuals from intensive surveillance confidently. Methods In this prospective, nested case–control study, maternal serum samples were collected between 20+0 ...
Matthews Silva Martins, Julyane N. S. Kaihara, Diego Fortes Salgueiro, Viviane Cunha Cardoso, Silvana Maria Quintana, Ricardo Carvalho Cavalli, Valerio Garrone Barauna, Valeria Cristina Sandrim   +7 more
wiley   +1 more source

A spatiotemporal single‐cell atlas of porcine development reveals regulatory dynamics and cellular targets of domestication

iMeta, EarlyView.
This study presents a cross‐tissue, single‐cell/single‐nucleus transcriptomic atlas spanning from prenatal to postnatal developmental stages in pig, characterizing 83 distinct cell types from 252,033 cells. Through the construction of cross‐tissue transcriptional regulatory networks and pseudotime trajectories, we revealed that organogenesis is driven ...
Rong Zhou, Zishuai Wang, Chenghao Hu, Shuhan Deng, Changyun Cai, Yanfang Wang, Shang‐Tong Li, Lijing Bai, Kui Li   +8 more
wiley   +1 more source

Evaluating the impact of therapeutic drug monitoring strategies on clinical outcomes in paediatric inflammatory bowel disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives The increasing incidence of inflammatory bowel disease (IBD) in paediatric populations underscores the importance of effective management strategies. Anti–tumor necrosis factor (anti‐TNF) agents, such as infliximab (IFX) and adalimumab (ADL), are key treatments for inducing and maintaining remission in IBD, but many patients ...
Karlotta Pauline Hubert, Sebastian Stricker, Jan De Laffolie   +2 more
wiley   +1 more source

Effects of genotype and environment on the physiochemical properties of Canadian oat varieties

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 3111-3121, 30 March 2025.
Abstract BACKGROUND The relationship between oat grain composition and physical attributes as influenced by oat genotype and Canadian growing environments was investigated. Thirty Canadian oat (Avena sativa L.) genotypes, grown in three Canadian growing locations (Brandon, Manitoba; Portage la Prairie, Manitoba; and Lacombe, Alberta) over 2 consecutive
Vanessa Alexander, Kirby T. Nilsen, Sijo Joseph, Trust Beta, Lovemore Nkhata Malunga   +4 more
wiley   +1 more source