Results 91 to 100 of about 635,476 (340)

Xylose Metabolism Perturbation in Yarrowia lipolytica for Efficient Succinic Acid Bioproduction from Lignocellulosic Biomass

Advanced Science, EarlyView.
This study engineers Yarrowia lipolytica to produce succinic acid (SA) from lignocellulosic biomass. Adaptive evolution and multi‐omics analysis identify regulators that alleviate xylose metabolic disorder. Multi‐copy integration of xylose metabolic genes resolves redox imbalances from a futile fatty acid cycle, producing high‐titer SA from corn stover
Yutao Zhong, Changyu Shang, Jinhong Gu, Huilin Tao, Xuemei Lu, Jin Hou, Zhiyong Cui, Qingsheng Qi   +7 more
wiley   +1 more source

Diversity of yeasts involved in the fermentation of tchoukoutou, an opaque sorghum beer from Benin [PDF]

, 2011
Opaque sorghum beers are traditional alcoholic beverages in several African countries. Known as tchoukoutou in Benin, the beer is often obtained from an uncontrolled fermentation. It is consumed in an actively fermenting state and has a sour taste.
Boekel, M.A.J.S., van, Hounhouigan, A.J.D., Kayode, A.P.P., Kotchoni, S.O., Linnemann, A.R., Nout, M.J.R., Vieira-Dalode, G.   +6 more
core   +2 more sources

The role and use of non-saccharomyces yeasts in wine production

, 2017
The contribution by the numerous grape-must-associated non-Saccharomyces yeasts to wine fermentation has been debated extensively. These yeasts, naturally present in all wine fermentations, are metabolically active and their metabolites can impact on ...
N. Jolly, O. Augustyn, I. S. Pretorius
semanticscholar   +1 more source

Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT

Advanced Science, EarlyView.
Zinc activates the ZNG1‐METAP1 complex to elevate intracellular SAM levels, which promotes PRMT5‐mediated symmetrical dimethylation of AKT at R391 and R15. This epigenetic modification facilitates AKT membrane translocation and mTORC2 activation, thereby enhancing epithelial proliferation and gut barrier integrity.
Chuanjiang Cai, Yining Zheng, Bo Sun, Guoyan Wang, Pengfei Li, Huijun Geng, Rongnuo Li, Miaomiao Zhu, Yuanyuan Zhu, Dingping Feng, Lei Chen, Guiyan Chu, Lu Deng, Shiyan Qiao   +13 more
wiley   +1 more source

The dynamics of genome replication using deep sequencing [PDF]

, 2013
Peer reviewedPublisher ...
Agier, Alessandro P.S. de Moura, Alvino, Besnard, Bouton, Breier, Carolin A. Müller, Celniker, Chang, Conrad A. Nieduszynski, Cosgrove, Crampton, de Moura, De Piccoli, Di Rienzi, Eaton, Feng, Friedman, Gilbert, Hoggard, Huang, Katsuhiko Shirahige, Kearsey, Knott, Knott, Koren, Koren, Liachko, Lian, Makiko Komata, Martin J. Blythe, McGuffee, Mechali, Mechali, Mesner, Michelle Hawkins, Muller, Nakato, Natsume, Newman, Ng, Nieduszynski, Palzkill, Raghuraman, Ray Wilson, Renata Retkute, Retkute, Retkute, Rhind, Rudolph, Ryuichiro Nakato, Sekedat, Sharma, Shirahige, Siow, Sunir Malla, Theis, Theis, Theis, Vujcic, Xu, Xu, Yabuki, Yamashita, Yoshikawa   +64 more
core   +3 more sources

Xylose Fermentation by Saccharomyces cerevisiae: Challenges and Prospects

International Journal of Molecular Sciences, 2016
Many years have passed since the first genetically modified Saccharomyces cerevisiae strains capable of fermenting xylose were obtained with the promise of an environmentally sustainable solution for the conversion of the abundant lignocellulosic biomass
D. N. Moysés, Viviane Castelo Branco Reis, J. R. M. de Almeida, L. M. D. de Moraes, F. Torres   +4 more
semanticscholar   +1 more source

Enhancing the β‐Oxidation‐Like Pathway for the Optimal Production of the Immunosuppressant Mycophenolic Acid

Advanced Science, EarlyView.
The most elaborate known example of β‐oxidation‐like pathway recruitment in fungi is reported, involving a 10‐step oxidative chain‐shortening cascade catalyzed by five dedicated enzymes to generate the pharmacophore of mycophenolic acid (MPA)—a novel clinical immunosuppressant. Our findings illustrate how nature repurposes catabolic enzymes for complex
Baoqiang Fan, Yinuo Liu, Lu‐ping Chi, Chaofan Yang, Shengying Li, Wei Zhang   +5 more
wiley   +1 more source

Genetic Basis of Ammonium Toxicity Resistance in a Sake Strain of Yeast: A Mendelian Case. [PDF]

, 2013
High concentrations of ammonium at physiological concentrations of potassium are toxic for the standard laboratory strain of Saccharomyces cerevisiae In the original description of this metabolic phenotype, we focused on the standard laboratory strains ...
Botstein, David, Dick, Cynthia, Hess, David C, Kruglyak, Leonid, Reisser, Cyrielle, Schacherer, Joseph   +5 more
core   +1 more source

MoMtg1 Acts as a Novel Transcriptional Repressor of MoSwi6 During Appressorium‐Mediated Penetration in the Rice Blast Fungus

Advanced Science, EarlyView.
Appressoria are specialized penetration structures for many plant pathogenic fungi, demanding precise cell cycle control. This study unveils MoMtg1 as a transcriptional repressor of MoSwi6, orchestrating MoCYC1 expression during turgor‐driven cell cycle progression to enable appressorium‐mediated penetration. Moreover, a small‐molecule inhibitor ZS1619
Xingyu Wang, Ting Zhang, Qi Li, Chang‐An Ji, Lin Huang, Mingzhi Zhang, Leiyun Yang, Xinyu Liu, Muxing Liu, Gang Li, Zhengguang Zhang, Haifeng Zhang   +11 more
wiley   +1 more source

A non-homogeneous dynamic Bayesian network with sequentially coupled interaction parameters for applications in systems and synthetic biology [PDF]

, 2012
An important and challenging problem in systems biology is the inference of gene regulatory networks from short non-stationary time series of transcriptional profiles.
Grzegorczyk, M., Husmeier, D.
core   +2 more sources