Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
Correction: Functional redundancy and formin-isoform independent localization of tropomyosin paralogs in Saccharomyces cerevisiae. [PDF]
PLOS Genetics Staff.
europepmc +1 more source
ABSTRACT The tRNA splicing endonuclease (TSEN) removes introns from precursor tRNAs (pre‐tRNAs) in eukaryotes and archaea, but the architecture and subunit organization of plant TSEN remain poorly defined. Here, we integrated in planta bimolecular fluorescence complementation (BiFC) assays with AlphaFold3 (AF3)‐based structural modeling, molecular ...
Mohammad Moniruzzaman +2 more
wiley +1 more source
Extracellular Metabolites from <i>Saccharomyces cerevisiae</i> Modulate the Growth and Fermentative Performance of <i>Kluyveromyces marxianus</i>. [PDF]
Gallardo-Rivera J +5 more
europepmc +1 more source
The continuing significance of chiral agrochemicals
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
Statement of Retraction: Easy efficient HDR-based targeted knock-in in <i>Saccharomyces cerevisiae</i> genome using CRISPR-Cas9 system. [PDF]
europepmc +1 more source
Safety and efficacy concerns in Indian probiotics: Insights from whole-genome sequencing and <i>in vitro</i> assessment. [PDF]
Madhumathi I +12 more
europepmc +1 more source
This graphical abstract summarizes the main strategies for incorporating natural antimicrobial agents into thermoplastic food packaging polymers, including melt processing, surface deposition, controlled release and chemical immobilization. It highlights the major classes of natural antimicrobials, key advantages such as microbial growth reduction and ...
Florence Akinmeye +4 more
wiley +1 more source
Synergistic effects of dietary RISCO-NUTRIFOUR probiotic on broiler performance, upregulation of intestinal immunoglobulin A and mucin-2 genes, enhancement of occludin expression, and downregulation of HSP70 under heat stress. [PDF]
Al-Abdullatif AA +7 more
europepmc +1 more source
Macroscopic Convective Fluid Flows Arising From Binding of Ions and Small Molecules to Proteins
The interaction of ions or small molecules with proteins causes convective flows due to the displacement of water from the hydration shell. As shown, the replacement of the nickel ion removed from urease by EDTA pre‐treatment results in binding‐induced convective fluid flow.
Shanid Babu Shrestha +4 more
wiley +1 more source

