A multi-omics systems toxicology framework reveals amino acid-mediated stress adaptation to deltamethrin exposure in a yeast model. [PDF]
Yavuz M +5 more
europepmc +1 more source
Rescue of pATOM36‐depleted T. brucei by human MTCH1/2 reveals common features of protein insertases
Human MTCH1 and MTCH2 (with an N‐terminal extension) functionally complement the loss of pATOM36 in T. brucei, indicating that these evolutionarily distant proteins recognize a common set of substrates and share fundamental principles of mitochondrial outer membrane protein insertion. Structural analyses reveal a common hydrophilic cavity, supporting a
Stephan Berger +4 more
wiley +1 more source
In silico prediction of metabolic trait robustness in microbial cells. [PDF]
Gu C, Mustonen V, Jouhten P.
europepmc +1 more source
As we age, cells gradually accumulate damage, which can contribute to disease and neurodegeneration. This review explores how two cellular recycling processes, mitophagy and nucleophagy, remove damaged mitochondria and nuclear material, respectively, to maintain cell health and long‐term neuronal homeostasis.
Maria Markaki, Nektarios Tavernarakis
wiley +1 more source
Exploring the potential of sequential fermentation with indigenous <i>Candida</i> sp. and <i>Saccharomyces cerevisiae</i> to enhance chemical profile and flavor characteristics of apricot wine. [PDF]
Han B +8 more
europepmc +1 more source
UbiB proteins mediate an ATP‐dependent decarboxylation step in bacterial ubiquinone biosynthesis
UbiB proteins are atypical protein kinase‐like enzymes essential for ubiquinone biosynthesis. Here, we demonstrate that bacterial UbiB proteins catalyze the O2‐dependent decarboxylation of ubiquinone precursors, a process linked to their ATPase activity.
Katayoun Kazemzadeh +12 more
wiley +1 more source
Effects of Lactobacillus Alone and in Combination With Saccharomyces as Alternatives to Antibiotics on Performance and Immunity in Laying Hens. [PDF]
Alam MJ +5 more
europepmc +1 more source
Lipid droplets (LD) act as cellular ‘garbage trucks’ that transport cytosolic protein aggregates to the vacuole for degradation in yeast. Protein aggregates are docked to lipid droplets in a triacylglycerol‐dependent manner, transported through the cytoplasm, and transferred to the insoluble protein deposit (IPOD) at the vacuole.
Christoph Reiter +15 more
wiley +1 more source
Safety and Effectiveness of Probiotic Preparations: A Contemporary Review. [PDF]
Shorabaev E +6 more
europepmc +1 more source
The harnessing potential of carboxymethyl beta glucan: A driver of skin repair
Carboxymethyl Beta‐Glucan (CM‐BG) drives skin repair through multifaceted actions, notably in wounded 3D models. It activates Dectin‐1 and mitigates inflammation (reducing pro‐inflammatory mediators, boosting anti‐inflammatory IL‐10) in cellular models, while enhancing epidermal differentiation and collagen I synthesis by fibroblasts across cellular ...
Caroline Pichon +4 more
wiley +1 more source

