The OBF1 protein and its DNA-binding site are important for the function of an autonomously replicating sequence in Saccharomyces cerevisiae. [PDF]
, 1989 Scott S. Walker +3 more
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The FEBS Journal, EarlyView.Sti1/Hop functions extend beyond scaffolding in the Hsp70‐Hsp90 chaperone complex to sequester misfolded proteins during cell stress. Consequently, imbalances between levels of Sti1/Hop relative to the rest of the proteostasis machinery negatively affect fitness and stress resilience. Sti1/Hop is a cochaperone that regulates Hsp70 and Hsp90 chaperones.
Gregory Lloyd Blatch +1 more
wiley +1 more source
The Hexokinase Isoenzyme PII of Saccharomyces cerevisiae is a Protein Kinase [PDF]
, 1989 Pilar Herrero +2 more
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Conserved function of a RasGEF‐mediated pathway in the metabolic compensation of the circadian clock
The FEBS Journal, EarlyView.Metabolic compensation of the circadian clock is essential for stabilizing the period of endogenous timekeeping in environments with significant nutrient fluctuations. In this study, we demonstrate that RasGEF (SOS1)‐mediated signaling, which is influenced by metabolic conditions, supports the robust function of the circadian clock under low glucose ...
Orsolya Sárkány +6 more
wiley +1 more source
Characterization of an estrogen-binding protein in the yeast Saccharomyces cerevisiae.
, 1984 Alan Burshell +4 more
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A guide to heat shock factors as multifunctional transcriptional regulators
The FEBS Journal, EarlyView.The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka +3 more
wiley +1 more source
Short coiled‐coil proteins from plants and metazoans – the ‘jacks of all trades’
The FEBS Journal, EarlyView.Short coiled‐coil proteins from plants and metazoans—true ‘jacks of all trades’—play supporting but crucial roles in cellular stress response, metabolism, autophagy, and membrane dynamics. Despite their small size and modest sequence conservation, proteins like plant LSUs and metazoan SCOCs showcase remarkable functional versatility shaped by evolution,
Agnieszka Sirko +2 more
wiley +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum. [PDF]
FEBS LettIn Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Karapanagioti F +3 more
europepmc +2 more sources
Purification of a protein binding to the CDEI subregion of Saccharomyces cerevisiae centromere DNA.
, 1989 Weidong Jiang, Peter Philippsen
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