Results 131 to 140 of about 139,200 (267)

Enhanced Separation of Intact Proteins and Proteoforms by CZE‐MS Using Sulfobetaine‐Modified Poly(α‐L‐lysine)‐Based Multilayer Coatings for EOF Adjustment

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Mass spectrometry–based top‐down protein analysis requires efficient separation. In the context of proteoform analysis, capillary zone electrophoresis (CZE) is very valuable. The resolution of two peaks in CZE can be increased when the absolute mobility of the counter‐directed electroosmotic flow (EOF) is close to the effective mobility of the
Alisa Höchsmann   +8 more
wiley   +1 more source

Supervised Learning of Protein Melting Temperature: Cross‐Species vs. Species‐Specific Prediction

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Protein melting temperatures are important proxies for stability, and frequently probed in protein engineering campaigns, for instance for enzyme discovery and protein optimization. With the emergence of large datasets of melting temperatures for diverse natural proteins, it has become possible to train models to predict this quantity, and the
Sebastián García López   +2 more
wiley   +1 more source

Protein glycosylation defects in the Saccharomyces cerevisiae mnn7 mutant class

open access: hybrid, 1989
L Ballou   +4 more
openalex   +1 more source

The serine palmitoyl transferase of plant pathogenic fungi: a promising new target for the development of novel crop protection solutions†

open access: yesPest Management Science, EarlyView.
High biological activity of pyridazine carboxamides against a wide range of Ascomycetes led to identification of a new biochemical target for agrochemical fungicides – serine palmitoyl transferase. Abstract BACKGROUND Plant pathogens pose a significant threat to global agriculture and, thus to world food supplies, requiring the development of ...
Lionel Nicolas   +13 more
wiley   +1 more source

Pervasive Divergence in Protein Thermostability is Mediated by Both Structural Changes and Cellular Environments. [PDF]

open access: yesMol Biol Evol
Walunjkar N   +8 more
europepmc   +1 more source

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