Results 191 to 200 of about 139,200 (267)

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

open access: yesThe FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický   +22 more
wiley   +1 more source

The bZIP3‐AS1 complex promotes CONSTANS‐induced FLOWERING LOCUS T activation in a daylength‐dependent manner

open access: yesJournal of Integrative Plant Biology, EarlyView.
The Arabidopsis bZIP3 protein works in conjunction with ASYMMETRIC LEAVES1 to facilitate the function of the CONSTANS protein in activating FLOWERING LOCUS T expression at the end of the day in a day length‐dependent manner. ABSTRACT Plants monitor daylength to synchronize their flowering time with their surroundings and thus maximize reproductive ...
Wonbok Lee   +10 more
wiley   +1 more source

Biochemical characterization of phosphoenolpyruvate carboxykinases from multiple species of brown algae

open access: yesJournal of Phycology, EarlyView.
Abstract Phosphoenolpyruvate carboxykinase (PEPCK) is involved in the conversion of phosphoenolpyruvate (PEP) to oxaloacetate (OAA). In addition to playing a role in gluconeogenesis in various organisms, PEPCK also functions in the C4 cycle to concentrate CO2 for photosynthesis in some C4 plants.
Jian‐qiang Jin   +3 more
wiley   +1 more source

Whole‐Genome Sequencing and Phenotyping Reveal Specific Adaptations of Lachancea thermotolerans to the Winemaking Environment

open access: yesMolecular Ecology, EarlyView.
ABSTRACT Adaptation to the environment plays an essential role in yeast evolution as a consequence of selective pressures. Lachancea thermotolerans, a yeast related to fermentation and one of the current trends in wine technology research, has undergone an anthropisation process, leading to a notable genomic and phenomic differentiation.
Javier Vicente   +5 more
wiley   +1 more source

Autophagy and the Mitochondrial Lon1 Protease Are Necessary for Botrytis cinerea Heat Adaptation

open access: yesMolecular Microbiology, EarlyView.
The destabilization of mitochondria due to the disruption of the Lon1 protease induces cellular damage, including reactive oxygen species (ROS) accumulation, impaired germination, and growth arrest. Activation of autophagy inhibits fungal growth and recycles damaged cellular components, potentially serving as a cytoprotective role downstream of the ...
Mingzhe Zhang   +4 more
wiley   +1 more source

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