Results 231 to 240 of about 137,997 (266)

Phylogenomics and functional annotation of 530 non-<i>Saccharomyces</i> yeasts from winemaking environments reveals their fermentome and flavorome. [PDF]

Stud Mycol
Franco-Duarte R, Fernandes T, Sousa MJ, Sampaio P, Rito T, Soares P.   +5 more
europepmc   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, Volume 599, Issue 12, Page 1749-1759, June 2025.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Understanding adaptation to fluconazole: comparative insights into tolerance and resistance in <i>Saccharomyces cerevisiae</i> and <i>Candida albicans</i>. [PDF]

Front Cell Infect Microbiol
Zheng L, Dong Y, Wang J, Jia Y, Wang W, Xu Y, Guo L.   +6 more
europepmc   +1 more source

Functional Biomaterials Derived from Protein Liquid–Liquid Phase Separation and Liquid‐to‐Solid Transition

Advanced Materials, Volume 37, Issue 22, June 5, 2025.
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li, Dea Ilhamsyah, Benedict Tai, Yi Shen   +3 more
wiley   +1 more source

IAT4, a New Indolamine N-Acetyltransferase in Saccharomyces cerevisiae Involved in Melatonin Biosynthesis. [PDF]

J Pineal Res
Planells-Cárcel A, Sánchez-Martí S, Muñiz-Calvo S, Guillamon JM.   +3 more
europepmc   +1 more source

A 3D‐Printed Microfluidic Sensor Platform for Online Bioprocess Monitoring

Advanced Sensor Research, Volume 4, Issue 6, June 2025.
A 3D‐printed microfluidic lab‐on‐a‐chip sensor platform is presented, compatible with various cultivation setups, that integrates sensors for pH, pO₂, pCO₂, glucose, lactate, and additionally features a sampling unit for small‐volume abstraction. With this platform, continuous real‐time monitoring of critical bioprocess parameters is enabled and ...
Christopher Heuer, Anton Enders, Steffen Winkler, Martin Klaßen, Thorsten Teutenberg, Janina Bahnemann   +5 more
wiley   +1 more source

Mining yeast diversity unveils novel targets for improved heterologous laccase production in Saccharomyces cerevisiae. [PDF]

Microb Cell Fact
Wong RWK, Foo M, Lay JRS, Wai TLT, Moore J, Dutreux F, Molzahn C, Nislow C, Measday V, Schacherer J, Mayor T.   +10 more
europepmc   +1 more source

KK2DP7 Stimulates CD11b+ Cell Populations in the Spleen to Elicit Trained Immunity for Anti‐Tumor Therapy

Advanced Science, Volume 12, Issue 23, June 20, 2025.
This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang, Lin Tang, Yusi Wang, Xuejing Zhou, Zhenyu Ding, Li Yang   +5 more
wiley   +1 more source

Rosmarinic Acid as Bioactive Compound: Molecular and Physiological Aspects of Biosynthesis with Future Perspectives. [PDF]

Cells
Jakovljević D, Warchoł M, Skrzypek E.
europepmc   +1 more source

Antioxidant properties and antimicrobial activity of selenium nanoparticles synthetized via Zambian medicinal herbs. [PDF]

PLoS One
Chilala P, Jurickova M, Pokorna Z, Motlova T, Horky P, Skalickova S.   +5 more
europepmc   +1 more source