Impact of limited solvent capacity on metabolic rate, enzyme activities, and metabolite concentrations of S. cerevisiae glycolysis [PDF]
, 2008 The cell's cytoplasm is crowded by its various molecular components, resulting in a limited solvent capacity for the allocation of new proteins, thus constraining various cellular processes such as metabolism.
Barabási, AL +3 more
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Dynamic Structure of Yeast Septin by Fast Fluctuation-Enhanced Structured Illumination Microscopy
Microorganisms, 2021 When Saccharomyces cerevisiae divides, a structure composed of different septin proteins arranged according to a certain rule is formed at the cell division site.
Longfang Yao +8 more
doaj +1 more source
Construction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases in malaria parasites [PDF]
, 2011 Background information The pathology causing stages of the human malaria parasite Plasmodium falciparum reside within red blood cells that are devoid of any regulated transport system.
Bourdoncle, P. +9 more
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Evaluation of Unconventional Protein Secretion by Saccharomyces cerevisiae and other Fungi
Cells, 2018 Development of proteome analysis of extracellular proteins has revealed that a wide variety of proteins, including fungal allergens are present outside the cell. These secreted allergens often do not contain known secretion signal sequences.
Natsuko Miura, Mitsuyoshi Ueda
doaj +1 more source
Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome. [PDF]
, 2019 Introns are a prevalent feature of eukaryotic genomes, yet their origins and contributions to genome function and evolution remain mysterious. In budding yeast, repression of the highly transcribed intron-containing ribosomal protein genes (RPGs ...
Ares, Manuel +8 more
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Prion protein gene polymorphisms in Saccharomyces cerevisiae [PDF]
Molecular Microbiology, 2003 SummaryThe yeast Saccharomyces cerevisiae genome encodes several proteins that, in laboratory strains, can take up a stable, transmissible prion form. In each case, this requires the Asn/Gln‐rich prion‐forming domain (PrD) of the protein to be intact.
Resende, Catarina +4 more
openaire +3 more sources
Microbial Cell Factories, 2007 The yeast Saccharomyces cerevisiae is a well-established model system for understanding fundamental cellular processes relevant to higher eukaryotic organisms.
Breinig Tanja +5 more
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Toward a molecular understanding of yeast silent chromatin : roles for H4K16 acetylation and the Sir3 C-terminus [PDF]
, 2012 Discrete regions of the eukaryotic genome assume a heritable chromatin structure that is refractory to gene expression. In budding yeast, silent chromatin is characterized by the loading of the Silent Information Regulatory (Sir) proteins (Sir2, Sir3 and
Oppikofer, Mariano
core +1 more source
Identification of novel human damage response proteins targeted through yeast orthology. [PDF]
PLoS ONE, 2012 Studies in Saccharomyces cerevisiae show that many proteins influence cellular survival upon exposure to DNA damaging agents. We hypothesized that human orthologs of these S.
J Peter Svensson +4 more
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G3: Genes, Genomes, Genetics, 2021 Life requires the oligomerization of individual proteins into higher-order assemblies. In order to form functional oligomers, monomers must adopt appropriate 3D structures.
Ashley S Denney +2 more
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