Results 11 to 20 of about 12,443 (164)

The LysR family transcriptional regulator ORF-L16 regulates spinosad biosynthesis in Saccharopolyspora spinosa [PDF]

Synthetic and Systems Biotechnology
Spinosad, a potent broad-spectrum bioinsecticide produced by Saccharopolyspora spinosa, has significant market potential. Despite its effectiveness, the regulatory mechanisms of spinosad biosynthesis remain unclear.
Xin Mu, Ru Lei, Shuqing Yan, Zixin Deng, Ran Liu, Tiangang Liu   +5 more
doaj   +4 more sources

Genome Sequence of the Spinosyns-Producing Bacterium Saccharopolyspora spinosa NRRL 18395 [PDF]

J Bacteriol, 2011
ABSTRACT Saccharopolyspora spinosa is a Gram-positive bacterium that produces spinosad, a well-known biodegradable insecticide that is used for agricultural pest control and has an excellent environmental and mammalian toxicological profile.
Pan Y, Yang X, Li J, Zhang R, Hu Y, Zhou Y, Wang J, Wang J, Zhu B.   +8 more
europepmc   +7 more sources

Some features of cultivation of the actinobacterium saccharopolyspora spinosa [PDF]

5th International Scientific Conference on Microbial Biotechnology, 2022
Purpose: Actinobacteria (actinomycetes) are in the center of attention because these bacteria produce a variety of natural drugs and other biologically active metabolites, including: antibiotics, enzymes, inhibitors. More than 22,000 biologically active secondary metabolites (including antibiotics) produced by microorganisms have been identified and ...
LUNGU, A.
openaire   +2 more sources

ARTP/NTG Compound Mutagenesis Improved the Spinosad Production and the Insecticidal Virulence of Saccharopolyspora Spinosa. [PDF]

Int J Mol Sci
Spinosad is an efficient and broad-spectrum environmentally friendly biopesticide, but its low yield in wild-type Saccharopolyspora spinosa limits its further application. ARTP/NTG compound mutagenesis was used in this study to improve the spinosad titer of S. spinosa and obtain a high-yield mutant—NT24.
Zhu Z, Chen W, Cao L, Xia Z, Rang J, Hu S, Xia L.   +6 more
europepmc   +4 more sources

Enhanced spinosad production in Saccharopolyspora spinosa by employing mannose as an extracellular carbon reservoir and optimizing acetyl-CoA supply pathway [PDF]

Synthetic and Systems Biotechnology
Spinosad, a potent broad-spectrum insecticidal polyketide produced by Saccharopolyspora spinosa, faces limitations in industrial-scale production due to inherent inefficiencies in its native biosynthetic pathways.
Zirong Zhu, Qin Zhao, Yan Zhu, Ling Shuai, Jun Li, Qing Liu, Xirong Liu, Shanrui Wang, Duo Jin, Zirui Dai, Liqiu Xia, Hongrong Liu, Jie Rang   +12 more
doaj   +2 more sources

Optimization of spinosad production by Saccharopolyspora spinosa YJY-12 and its application in controlling Eggplant Thrips [PDF]

Scientific Reports
In this study, a new isolated strain YJY-12 with high yield of spinosad was isolated and its fermentation conditions for spinosad production was optimized. It was preliminary identified by morphological and molecular biology analysis to be S. spinosa YJY-
Jiewei Tian, Yanrui Ma, Guangpeng Liu, Xiufeng Long   +3 more
doaj   +2 more sources

Coordinated regulation of propionyl-CoA carboxylase subunits drives precursor flux optimization in spinosad production [PDF]

Frontiers in Microbiology
Spinosad, a natural agricultural pesticide produced by Saccharopolyspora spinosa, has gained global attention owing to its potent insecticidal properties and environmental compatibility.
Ziyuan Xia, Xiaomin Li, Xirong Liu, Li Cao, Duo Jin, Zirui Dai, Baolong Bai, Qian Liu, Jie Rang, Zirong Zhu, Liqiu Xia   +10 more
doaj   +2 more sources

dTSR enables efficient improvement of heterologous production of spinosad in Saccharopolyspora erythraea [PDF]

Synthetic and Systems Biotechnology
Spinosad (spinosyns A and D) is a highly effective and environmentally friendly insecticide widely used for pest control. However, the difficulty of genetic manipulation in the original strain, Saccharopolyspora spinosa, has hindered improvements in ...
Weijun He, Jin Lü, Lulu Bai, Zixin Deng, Meifeng Tao   +4 more
doaj   +2 more sources

Insecticidal Evaluation of Spinosad Against the Hide Beetle, Dermestes maculatus DeGeer (Coleoptera: Dermestidae) [PDF]

Insects
Spinosad, Saccharopolyspora spinosa, is widely used as a stored product protectant. However, its efficacy against the hide beetle Dermestes maculatus DeGeer (Coleoptera: Dermestidae), a major pest of dried animal-based materials, remains underexplored ...
Shakila Khatun Bristy, Md. Nadim Aktar, Ataul Ahad, Md. Saiful Islam, Paraskevi Agrafioti, Christos G. Athanassiou, Md. Mahbub Hasan   +6 more
doaj   +2 more sources

New Active Ingredients for Sustainable Modern Chemical Crop Protection in Agriculture. [PDF]

ChemSusChem
To ensure sustainability in crop protection, development of modern agrochemicals with improved selectivity, efficacy and environmental profile is essential. This ambitious goal can be achieved, for example, by considering halogen‐containing motifs or sterogenic centers in an active ingredient, having a significant influence on its physico‐chemical ...
Jeschke P.
europepmc   +2 more sources