Results 21 to 30 of about 12,443 (164)
A 108-kb genomic DNA region of Saccharopolyspora spinosa NRRL 18395, producer of the agriculturally important insecticidal antibiotics spinosyns, has been cloned, sequenced and analyzed to reveal clustered genes encoding a type I polyketide synthase (PKS) complex. The genes for the PKS are flanked by genes encoding homologs of enzymes that are involved
Zirkle, Ross +4 more
openaire +3 more sources
A New Medium for Improving Spinosad Production by Saccharopolyspora spinosa. [PDF]
Spinosad (a mixture of spinosyns A and D) is a unique natural pesticide produced by Saccharopolyspora spinosa. With regard to attempts to improve S. spinosa by classical mutagenesis, we propose that the bottleneck of screening out high-spinosad-production strains is probably caused by the fermentation media.The current study aimed to identify a new ...
Guojun Y +4 more
europepmc +4 more sources
Genome-scale metabolic network reconstruction of Saccharopolyspora spinosa for spinosad production improvement. [PDF]
Spinosad is a macrolide antibiotic produced by Saccharopolyspora spinosa with aerobic fermentation. However, the wild strain has a low productivity. In this article, a computational guided engineering approach was adopted in order to improve the yield of spinosad in S.
Wang X, Zhang C, Wang M, Lu W.
europepmc +4 more sources
Metabolic engineering of rational screened Saccharopolyspora spinosa for the enhancement of spinosyns A and D production. [PDF]
Spinosyns A and D are potent ingredient for insect control with exceptional safety to non-target organisms. It consists of a 21-carbon tetracyclic lactone with forosamine and tri-O-methylated rhamnose which are derived from S-adenosylmethionine. Although previous studies have revealed the involvement of metK1 (S-adenosylmethionine synthetase), rmbA ...
Jha AK +5 more
europepmc +4 more sources
This study verified the efficiency of ovitraps combined with Saccharopolyspora spinosa and Bacillus thuringiensis israelensis for monitoring Aedes aegypti and Aedes albopictus in laboratory and field conditions. In the laboratory, for A.
Maxcilene da Oliveira +4 more
doaj +1 more source
Domenico Spinosa, Not only Movie: Kracauer’s Reading of Troeltsch and Weber at the Time of the Wissenschaftskrisis. Preliminary Note on a Case Study.
DOMENICO SPINOSA
core +2 more sources
Genome Combination Improvement Strategy Promotes Efficient Spinosyn Biosynthesis in <i>Saccharopolyspora spinosa</i>. [PDF]
Spinosyns are secondary metabolites produced by Saccharopolyspora spinosa known for their potent insecticidal properties and broad pesticidal spectrum. We report significant advancements in spinosyn biosynthesis achieved through a genome combination improvement strategy in S. spinosa.
Xia Z +6 more
europepmc +4 more sources
Comparative Proteomic Analysis of saccharopolyspora spinosa SP06081 and PR2 strains reveals the differentially expressed proteins correlated with the increase of spinosad yield. [PDF]
Background Saccharopolyspora spinosa produces the environment-friendly biopesticide spinosad, a mixture of two polyketide-derived macrolide active ingredients called spinosyns A and D.
Luo Y +7 more
europepmc +2 more sources
Complete genome sequence of butenyl-spinosyn-producing Saccharopolyspora strain ASAGF58
Purpose This study aimed to analyze the complete genome sequence of the butenyl-spinosyn-producing strain Saccharopolyspora sp. ASAGF58, isolated from Zhejiang province.
Chao Guo +3 more
doaj +1 more source
Bacteria of the genus Saccharopolyspora produce important polyketide antibiotics, including erythromycin A (Sac. erythraea) and spinosad (Sac. spinosa). We herein report the development of an industrial erythromycin-producing strain, Sac.
Jin Lü +10 more
doaj +1 more source

