Results 21 to 30 of about 140,214 (231)

The Relationship of Marital Satisfaction and Life Satisfaction with Spiritual Orientation: The Mediating Role of Sacrifice and Sensitivity [PDF]

Spiritual Psychology and Counseling, 2019
The purpose of this research is to test the proposed structural model related to the mediating role of sensitivity and sacrifice on the relationship of marital satisfaction and life satisfaction with married individuals’ spiritual orientations.
Mine Sayın, İbrahim Halil Demir, Füsun Ekşi   +2 more
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Mathematical Analysis of Malaria Epidemic: Asymptotic Stability With Cost-Effectiveness Study

Journal of Applied Mathematics
Malaria is an old, curable vector-borne disease that is devastating in the tropics and subtropical regions of the world. The disease has unmatched complications in the human host, especially in children.
Sacrifice Nana-Kyere, Baba Seidu, Kwara Nantomah   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Cultes de fertilité chez les Drung du Yunnan (Chine)

Moussons, 2012
Among the Drung of Yunnan, the absence of any clearly identifiable territorial rituals calls into question the relationship between ancestrality, territory and political power within the framework of a common ritual goal : achieving fertility.
Stéphane Gros
doaj   +1 more source

Candomblé rituals and food practices in Italy and Brazil: an ethnographic comparison

Antropolítica : Revista Contemporânea de Antropologia, 2020
This paper focuses on the relationship between food practices, preparation of Candomblé ritual offerings and performance of rituals in a transnational case study. My interest here is to consider two ethnographic accounts of Candomblé rituals in Italy and
Giovanna Capponi
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Sacrifice

, 2023
Abstract This chapter considers the meaning of sacrifice in the context of military families. It examines the notion of the family and the military as ‘greedy institutions’ which place considerable, and often competing, demands on service personnel.
openaire   +2 more sources

Az erőszak, a dominanciaigény és az áldozatállító hatásmechanizmus individuális és társadalmi vonatkozása

Studia Universitatis Babeş-Bolyai. Theologia Reformata Transylvanica
The Individual and Social Aspects of Violence, the Desire for Dominance, and the Mechanisms of Victimization. Some Anthropological Perspectives. Where does violence come from? Is it an inherent or a learned trait?
Szabolcs KOVÁCS
doaj   +1 more source