Results 41 to 50 of about 144,166 (265)
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Hair and Sacrifice in the Andean World, as deduced by biomolecular approaches
An individual’s first haircut is considered to be a major milestone in many world cultures and religions even today. It is interesting to note therefore that children placed as Inca child sacrifices in shrines on a number of the principal mountains in ...
Andrew Wilson
doaj +1 more source
Kurban Bagi Orang Toraja Dan Kurban Dalam Alkitab
: The author raises this title departs from concerns about the problems that occur in the life of the Toraja people, especially regarding the culture of mantunu.
Ascteria Paya Rombe
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
A WOMAN UNITED WITH THE SACRIFICE OF CHRIST – BLESSED KLEMENSA STASZEWSKA OSU (1890–1943)
The aim of this article is to examine the charism of Blessed Klemensa Staszewska, with which she was endowed by God, and its relevance to all believers.
Anna Emmanuela Klich
doaj +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
In a climate of intense political struggles between the clergy and the Parliament, on January 5, 1757, Damiens attempted to fatally strike Louis XV. The event holds an unprecedented symbolic importance, and despite the king’s attempts to silence the ...
Dario Maria Nicolosi
doaj +1 more source
Iphigenia in Tauris enables us to examine the original way in which Euripides uses the myth of the Atreids and the history of the family curse to develop philosophical and religious ideas.
Christine Amiech
doaj +1 more source
Powder metal processing provides scalable advantages in nanoporous (np) metal development. Mechanical alloying is used to produce unique precursors for hybrid nanopore formation by oxide reduction and dealloying. As demonstrated in np Ag, this approach improves process efficiency while promoting smaller ligaments and larger pores, both of which are ...
Mark A. Atwater, Oliver A. Fowler
wiley +1 more source

