Results 21 to 30 of about 144,423 (265)
This paper deals with the theme of giving away the body or parts of it. This theme is frequent in Buddhist literature, but also finds expression in the real life custom, attested in India and more so in China, of burning one’s own body as an act of religious fervour.
openaire +2 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Mathematical Analysis of Malaria Epidemic: Asymptotic Stability With Cost-Effectiveness Study
Malaria is an old, curable vector-borne disease that is devastating in the tropics and subtropical regions of the world. The disease has unmatched complications in the human host, especially in children.
Sacrifice Nana-Kyere +2 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
L’article se concentre sur la figure du guide de haute montagne, acteur majeur de l’alpinisme et héros populaire. Depuis la naissance du « Bergfilm » après la première mondiale, du cinéma muet au cinéma parlant, les stéréotypes narratifs et les éléments ...
Rémy Pithon
doaj +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Laughter Closed up in Horror: The Case of the Hungarian Ballad about a Walled-up Woman
Laughter Closed up in Horror: The Case of the Hungarian Ballad about a Walled-up Woman The paper is dedicated to a paradox. By approaching the topic of violence, I am actually trying to answer the question of whether and how it is possible to combine ...
Leszek Hensel
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source

