Results 31 to 40 of about 144,166 (265)

Buddhism and sacrifice [PDF]

open access: yes, 2012
This paper deals with the theme of giving away the body or parts of it. This theme is frequent in Buddhist literature, but also finds expression in the real life custom, attested in India and more so in China, of burning one’s own body as an act of religious fervour.
openaire   +2 more sources

"THE FULL SACRIFICE" [PDF]

open access: yesJournal of the American Medical Association, 1917
To the Editor: —Your editorial inThe Journal, October 20, p. 1355, entitled "The Full Sacrifice," strikes home. I am guilty; and yet I cannot bow gracefully to the charge of neglecting my duty. Surely I have done no bargaining. Indeed, on numerous occasions I have expressed my willingness to do anything I am asked to do.
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Mathematical Analysis of Malaria Epidemic: Asymptotic Stability With Cost-Effectiveness Study

open access: yesJournal of Applied Mathematics
Malaria is an old, curable vector-borne disease that is devastating in the tropics and subtropical regions of the world. The disease has unmatched complications in the human host, especially in children.
Sacrifice Nana-Kyere   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Le guide de montagne dans les fictions cinématographiques : quelques figures fondatrices et paradigmatiques (1915—1945)

open access: yesBabel: Littératures Plurielles, 2010
L’article se concentre sur la figure du guide de haute montagne, acteur majeur de l’alpinisme et héros populaire. Depuis la naissance du « Bergfilm » après la première mondiale, du cinéma muet au cinéma parlant, les stéréotypes narratifs et les éléments ...
Rémy Pithon
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Laughter Closed up in Horror: The Case of the Hungarian Ballad about a Walled-up Woman

open access: yesSlavia Meridionalis
Laughter Closed up in Horror: The Case of the Hungarian Ballad about a Walled-up Woman The paper is dedicated to a paradox. By approaching the topic of violence, I am actually trying to answer the question of whether and how it is possible to combine ...
Leszek Hensel
doaj   +1 more source

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