Results 51 to 60 of about 878,789 (291)
Philippe Le Guillou rend hommage à Montherlant dont l’œuvre a incarné pour lui à la fois un appel à étreindre la beauté du monde, et une exigence radicale, éthique et romaine.
Philippe Le Guillou
doaj +1 more source
The Five Main Themes of the Old Testament [PDF]
Definition and history of the Old Testament themes of covenant, kingship, grace, sacrifice, and ...
Mumme, Laura E.
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
“If You Could Die…”: Hart Crane’s “Accursed Share” in Mexico
This article explores the “spirit of sacrifice” and the influence of Aztec religion, as analyzed by Georges Bataille in various writings, on two poems written by Hart Crane in Mexico shortly before his suicide.
Beatrice Pire
doaj +1 more source
Covenant, Kingship, Grace, Sacrifice, and Prophetism in the Old Testament [PDF]
This essay examines the major themes of covenant, kingship, grace, sacrifice, and prophetism that reoccur throughout the Old Testament and contribute to a proper understanding of the ancient biblical text.
Scott, Rickie S
core +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source

