Results 51 to 60 of about 7,994 (216)

Measuring the Impact: MRI Response of Sacroiliac Joints to TNF Inhibitors in Youth with Axial Disease

Arthritis &Rheumatology, Accepted Article.
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes in youth with axial juvenile spondyloarthritis (axJSpA) initiating TNF inhibitor (TNFi).
Timothy G. Brandon, Rui Xiao, Daniel J. Lovell, Edward Oberle, Matthew L. Stoll, Nancy A. Chauvin, Michael L. Francavilla, Walter P. Maksymowych, Pamela F. Weiss   +8 more
wiley   +1 more source

Increased prevalence of pelvic venous congestion sign on sacroiliac MRI in women with clinically suspected sacroiliitis

İstanbul Kuzey Klinikleri, 2020
OBJECTIVE: To compare the prevalence of pelvic venous congestion (PVC) sign on sacroiliac and hip MRI in women of reproductive age as a possible cause of pain mimicking sacroiliitis.
Ahmet Peker, Gozde Tokatli, Ali Balci, Isil Basara Akın, Canan Altay, Gercek Can   +5 more
doaj   +1 more source

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

Arthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

Artificial intelligence for the detection of sacroiliitis on magnetic resonance imaging in patients with axial spondyloarthritis

Frontiers in Immunology, 2023
BackgroundMagnetic resonance imaging (MRI) is important for the early detection of axial spondyloarthritis (axSpA). We developed an artificial intelligence (AI) model for detecting sacroiliitis in patients with axSpA using MRI.MethodsThis study included ...
Seulkee Lee, Uju Jeon, Ji Hyun Lee, Seonyoung Kang, Hyungjin Kim, Jaejoon Lee, Myung Jin Chung, Myung Jin Chung, Hoon-Suk Cha   +8 more
doaj   +1 more source

Evaluating Associations Between Ankylosing Spondylitis, Torque Teno Virus and Polymorphisms in Interleukin 6 and Vitamin D Receptor Genes

International Journal of Immunogenetics, EarlyView.
ABSTRACT The etiology of ankylosing spondylitis (AS) is complex and not yet fully understood. Interleukin‐6 (IL‐6), vitamin D and the vitamin D receptor (VDR) play an important role in modulating immune response, and Torque teno virus is considered a marker of immune status. This case–control study aimed to investigate the predisposition to AS. A total
Dănuț Cimponeriu, Lavinia‐Mariana Berca, Irina Radu, Mihai Toma, Remus Nica, Silvia Nica, Roxana Măciucă   +6 more
wiley   +1 more source

Added Advantages of DWI MR Imaging and ADC Mapping in the Diagnosis of Active Sacroiliitis of Axial Seronegative SpA

Indian Journal of Rheumatology
Aim: To evaluate the effectiveness of diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) mapping in diagnosing active sacroiliitis in patients with axial seronegative spondyloarthropathy (SpA).
Deb K. Boruah, Rebecca R. Marak, Pallavi Gogoi, Bidyut B. Gogoi, Pranjal Phukan, Kalyan Sarma, Shivam Angiras, Halimuddin Ahmed   +7 more
doaj   +1 more source

Defining Bath Ankylosing Spondylitis Disease Activity Index Cut‐off Values for Disease Activity States in a Multinational European Cohort of Patients With Axial Spondyloarthritis

ACR Open Rheumatology, Volume 7, Issue 12, December 2025.
Objective The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) is widely used for assessing disease activity in patients with axial spondyloarthritis (axSpA), particularly in settings where markers of inflammation are unavailable. As no consensus on BASDAI cut‐off values exists for disease activity states in axSpA, we aimed to develop and ...
Stylianos Georgiadis, Lykke Midtbøll Ørnbjerg, Brigitte Michelsen, Tore K. Kvien, Mehrdad Shoae Kazemi, Jakub Závada, Karel Pavelka, Bente Glintborg, Anne Gitte Loft, Andreas Reich, Anne C. Regierer, Ana Maria Rodrigues, Maria José Santos, Jarno Rutanen, Laura Kuusalo, Adrian Ciurea, Michael J. Nissen, Bjorn Gudbjornsson, Ólafur Pálsson, Žiga Rotar, Katja Perdan Pirkmajer, Daniela Di Giuseppe, Mikkel Østergaard, Merete Lund Hetland   +23 more
wiley   +1 more source

Expert consensus on early diagnosis and treatment of psoriatic arthritis (2025 edition)

Rheumatology &Autoimmunity, Volume 5, Issue 4, Page 241-257, December 2025.
Psoriatic arthritis (PsA) is a chronic inflammatory musculoskeletal disease associated with psoriasis. PsA is characterized by diverse clinical manifestations and often follows a protracted, relapsing course, potentially leading to joint deformity and disability.
Ranran Yao, Lin Cai, Liling Xu, Yuhui Li, Yuan Jia, Yin Su, Chinese Expert Consensus Research Group on Early Recognition, Diagnosis and Treatment of Psoriatic Arthritis   +7 more
wiley   +1 more source

Biologic‐Induced Paradoxical Psoriatic Alopecia: A Systematic Review

Australasian Journal of Dermatology, Volume 66, Issue 8, Page 441-447, December 2025.
ABSTRACT A systemic review was completed of primary research articles reporting patient outcomes in paradoxical psoriatic alopecia in association with biologic therapy. Our search strategy identified 96 patients from 45 studies in addition to our own case.
Yaron Gu, Deshan F. Sebaratnam, Mani Makhija, Joshua Farrell   +3 more
wiley   +1 more source

Successful Treatment of Post‐SARS‐CoV‐2 Infection Reactive Arthritis With Secukinumab: A Case Report and Literature Review

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT This case describes a rare occurrence of post‐SARS‐CoV‐2 infection reactive arthritis with psoriasiform lesions. The patient failed to respond to conventional therapies but responded well to secukinumab, underscoring that it may be a valuable treatment for refractory post‐SARS‐CoV‐2 infection reactive arthritis when conventional therapies fail.
Qi Zhao, Tianyu Yao, Danyue He, Jie Hu, Yulin Wang, Ruyi Wang, Yiyang Hu, Chengyu Li, Jia Cai, Xiangning Li, Lili Tang, Xing Fan   +11 more
wiley   +1 more source