Results 31 to 40 of about 5,523,377 (316)

December 2019-Printed Issue

open access: yesPatient Safety, 2019
We are proud to announce the publication of the second issue of our journal, Patient Safety. You can read it now at no charge at PatientSafetyJ.com or download a PDF.
Patient Safety Authority
doaj   +1 more source

Safety and activity of anti-PD-L1 antibody in patients with advanced cancer.

open access: yesNew England Journal of Medicine, 2012
BACKGROUND Programmed death 1 (PD-1) protein, a T-cell coinhibitory receptor, and one of its ligands, PD-L1, play a pivotal role in the ability of tumor cells to evade the host's immune system.
J. Brahmer   +25 more
semanticscholar   +1 more source

June 2020-Printed Issue

open access: yesPatient Safety, 2020
The summer 2020 issue of Patient Safety is available to read and download at no charge. Each issue of Patient Safety delivers new evidence-based research and data analytics, engaging editorials, inspiring stories from patients and families, and ...
Patient Safety Authority
doaj   +1 more source

Scientific support for preparing an EU position for the 45th Session of the Codex Committee on Pesticide Residues (CCPR) [PDF]

open access: yesEFSA Journal, 2013
In accordance with Article 43 of Regulation (EC) No 396/2005, EFSA received a request from the European Commission to provide support for the preparation of the EU position for the 45th session of the Codex Committee on Pesticide Residues (CCPR). In 2012,
European Food Safety Authority
doaj   +1 more source

End-to-End Safe Reinforcement Learning through Barrier Functions for Safety-Critical Continuous Control Tasks [PDF]

open access: yesAAAI Conference on Artificial Intelligence, 2019
Reinforcement Learning (RL) algorithms have found limited success beyond simulated applications, and one main reason is the absence of safety guarantees during the learning process.
Richard Cheng   +3 more
semanticscholar   +1 more source

The REporting of A Disproportionality Analysis for DrUg Safety Signal Detection Using Individual Case Safety Reports in PharmacoVigilance (READUS-PV): Explanation and Elaboration

open access: yesDrug Safety
In pharmacovigilance, disproportionality analyses based on individual case safety reports are widely used to detect safety signals. Unfortunately, publishing disproportionality analyses lacks specific guidelines, often leading to incomplete and ambiguous
M. Fusaroli   +33 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Dupilumab Efficacy and Safety in Moderate‐to‐Severe Uncontrolled Asthma

open access: yesNew England Journal of Medicine, 2018
BACKGROUND Dupilumab is a fully human anti–interleukin‐4 receptor α monoclonal antibody that blocks both interleukin‐4 and interleukin‐13 signaling. We assessed its efficacy and safety in patients with uncontrolled asthma.
M. Castro   +26 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Considerations on the applicability of OECD TG 453 to whole food/feed testing [PDF]

open access: yesEFSA Journal, 2013
Upon request from the European Commission, the European Food Safety Authority prepared a scientific report that would aid the future establishment of protocols for chronic toxicity and/or carcinogenicity studies in rodents with whole food/feed.
European Food Safety Authority
doaj   +1 more source

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