Results 81 to 90 of about 1,053,024 (263)

Efficacy and safety of transanal endoscopic microsurgery for early rectal cancer: a meta-analysis

Frontiers in Oncology
BackgroundThe gold standard for the treatment of rectal cancer is radical surgery with total mesorectal excision (TME). As one of the alternatives to radical surgery, local resection has been proposed for the treatment of early rectal cancer. The purpose
Chunqiang Wang, Tianye Huang, Xuebing Wang   +2 more
doaj   +1 more source

Safety and efficacy of Monteban® G100 (narasin) for chickens for fattening

EFSA Journal, 2018
The feed additive Monteban® G100, containing the active substance narasin, an ionophore anticoccidial, is intended to control coccidiosis in chickens for fattening at a dose of 60–70 mg/kg complete feed. Narasin is produced by fermentation.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Maryline Kouba, Mojca Kos Durjava, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Gabriele Aquilina, Georges Bories, Paul Brantom, Pier Sandro Cocconcelli, Ingrid Halle, Boris Kolar, Pieter Wester, Patrick van Beelen, Orsolya Holczknecht, Maria Vittoria Vettori, Jürgen Gropp   +28 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Efficacy and safety of the phytotherapeutic drug Canephron® N in prevention and treatment of urogenital and gestational disease: review of clinical experience in Eastern Europe and Central Asia

Research and Reports in Urology, 2013
CorrigendumNaber KG. Research and Reports in Urology. 2013;5:39–46.Page 42, a new first sentence should be added to the Conclusion section as follows:"The three months administration of the herbal remedy for prevention of acute pyelonephritis in ...
Naber KG
doaj  

Comparison of robotic AI-assisted and manual pedicle screw fixation for treating thoracolumbar fractures: a retrospective controlled trial

Frontiers in Bioengineering and Biotechnology
ObjectiveTo compare the clinical efficacy and screw placement accuracy of robot artificial intelligence (AI)-assisted percutaneous screw fixation and conventional C-arm-assisted percutaneous screw fixation (manual placement) in the treatment of ...
Xun Xiao, Xun Xiao, XingKun Wang, XingKun Wang, Bin Meng, Bin Meng, Xin Pan, Hua Zhao   +7 more
doaj   +1 more source

Hypnotic Efficacy and Safety [PDF]

Sleep, 1981
W B, Mendelson, J C, Gillin, W C, Dement
openaire   +2 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Efficacy and safety of direct oral anticoagulants versus warfarin in patients with atrial fibrillation and liver disease: an updated systematic review and meta-analysis

Archives of Medical Science: Atherosclerotic Diseases
Introduction Although previous meta-analyses have explored the efficacy and safety of direct oral anticoagulants (DOAC) compared to warfarin in patients with atrial fibrillation (AFib) and liver disease, recent studies and emerging data necessitate a re ...
Riya Bhagwan, Rushaan Ahmed, Saad Ahmed Idrees, Saad Javaid, Roha Mazhar, Rahima Tauqeer, Mushood Ahmed, Satesh Kumar, Mahima Khatri, Ashish Gupta, Ramachandra Ramkumar, Mudassar Baig, Peter Collins, Raheel Ahmed   +13 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Safety and efficacy of tofacitinib in children with ulcerative colitis complicated with arthropathy: a single-center study

Frontiers in Pediatrics
ObjectivesTofacitinib is an oral Janus kinase (JAK) inhibitor initially used for the treatment of arthritis. It demonstrated to effectively induce and maintain remission in adults with inflammatory bowel disease (IBD).
Shijian Miao, Shengnan Wang, Wenhui Hu, Ying Huang, Yu Shi   +4 more
doaj   +1 more source