Results 61 to 70 of about 1,053,024 (263)
Cellulose Nanocrystals for Skin Barrier Protection by Preparing a Versatile Foundation Liquid
ACS Omega, 2021 Jie Tang +6 more
doaj +1 more source
Drug, Healthcare and Patient Safety, 2010 Adie Viljoen1, Anthony S Wierzbicki21Lister Hospital, Stevenage, Hertfordshire, UK; 2Guy’s and St Thomas Hospitals, London, UKAbstract: Statins form the cornerstone of pharmaceutical cardiovascular disease prevention.
Adie Viljoen, Anthony S Wierzbicki
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
International Journal of COPD, 2014 Walter Vincken,1 Joseph Aumann,2 Hungta Chen,3 Michelle Henley,3 Danny McBryan,4 Pankaj Goyal4 1Respiratory Division, University Hospital, UZ Brussel, Free University of Brussels, Brussels, Belgium; 2Longartsenpraktijk, Prins Bisschopssingel, Hasselt ...
Vincken W +5 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Efficacy, safety, and patient acceptability of the etonogestrel and ethinyl estradiol vaginal ring
Open Access Journal of Contraception, 2014 Iñaki Lete, Maialen Pérez de Arrilucea, María Rodríguez, Eskerne BelloDepartment of Gynecology, University Hospital Araba, Vitoria, Spain Abstract: The contraceptive vaginal ring (CVR) is a combined hormonal contraceptive ...
Lete I +3 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Clinical Ophthalmology, 2014 Yoshikawa K, Kozaki J, Maeda H. Efficacy and safety of brinzolamide/timolol fixed combination compared with timolol in Japanese patients with open-angle glaucoma or ocular hypertension. Clin Ophthalmol.
Yoshikawa K, Kozaki J, Maeda H
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Early‐Phase Research in Pediatric Neuro‐Oncology
Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source