The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Real-world safety assessment of burosumab: a pharmacovigilance study utilizing the FDA adverse event reporting system. [PDF]
Chen T, Liang M.
europepmc +1 more source
Advancing the implementation of artificial intelligence in regulatory frameworks for chemical safety assessment by defining robust readiness criteria. [PDF]
de Paula Souza J +20 more
europepmc +1 more source
Screening, Safety Assessment, and Process Optimization of Lactic Acid Bacteria from Traditional Yak Yogurt as Adjunct Cultures. [PDF]
Shuang W +5 more
europepmc +1 more source
Cannabis-based extract for managing pain in dogs with osteoarthritis: efficacy and safety assessment. [PDF]
Griebeler NM +12 more
europepmc +1 more source
Radiometric and safety assessment of a 'low-level red-light' myopia control device. [PDF]
Richards J +4 more
europepmc +1 more source
Comprehensive Analysis of Free BDPE Content in Commercial Hyaluronic Acid Fillers: Implications for Safety Assessment and Regulatory Standards. [PDF]
Kim CJ +7 more
europepmc +1 more source
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Abstract Safety assessments, risk analysis studies and emergency management evaluations are increasingly used for on- and offshore industrial installations with hazardous material. TNO has a broad experience in the development and application of effect and consequence modelling, reliability engineering methods and accident analysis and ...
Pietersen, C.M., Engelhard, W.F.J.M.
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Safety Assessment of Lactate Esters
Regulatory Toxicology and Pharmacology, 1998Lactate esters have an oral LD50 greater than 2000 mg/kg and the inhalation LC50 is generally above 5000 mg/m3 and they may be potential eye and skin irritants, but not skin sensitizers. No evidence of teratogenicity or maternal toxicity was observed in an inhalation (2-ethylhexyl-l-lactate) or dermal study (ethyl-l-lactate).
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