Results 61 to 70 of about 3,040,361 (309)

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Dietary Exposure and Risk Assessment for L-Ergothioneine in China

open access: yesFoods
L-Ergothioneine (L-EGT), a naturally occurring thiol compound abundant mainly in edible fungi, is increasingly regarded as a potentially beneficial bioactive constituent. However, population-level exposure data remain limited.
Sheng Ma   +8 more
doaj   +1 more source

Comparative study on genotoxicity methods between OECD Test guidelines and GB15193

open access: yesZhongguo shipin weisheng zazhi, 2022
ObjectiveThe purpose of this study is to compare genotoxicity methods between OECD test guidelines and China food safety standards(GB15193).MethodsMain parameters of related genotoxicity methods in OECD Testing Guidelines and GB 15193 standards were ...
ZHANG Xiaopeng   +3 more
doaj   +1 more source

Sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma [PDF]

open access: yes, 2019
Background: Sublingual allergen immunotherapy (SLIT) has been demonstrated to be both clinically efficacious and safe. However, in line with the current regulatory guidance from the European Medicines Agency, allergen immunotherapy (AIT) products must ...
Bachert, Claus   +10 more
core   +2 more sources

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka   +7 more
wiley   +1 more source

Patient safety competencies in undergraduate nursing students: a rapid evidence assessment [PDF]

open access: yes, 2016
Aims To identify patient safety competencies, and determine the clinical learning environments that facilitate the development of patient safety competencies in nursing students.
Bagnasco, Annamaria   +8 more
core   +2 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Environmental assessment overview [PDF]

open access: yes, 1980
The assessment program has as its objectives: to identify the environmental issues associated with the SPS Reference System; to prepare a preliminary assessment based on existing data; to suggest mitigating strategies and provide environmental data and ...
Valentino, A. R.
core   +1 more source

QuantUM: Quantitative Safety Analysis of UML Models

open access: yes, 2011
When developing a safety-critical system it is essential to obtain an assessment of different design alternatives. In particular, an early safety assessment of the architectural design of a system is desirable.
A. Aziz   +23 more
core   +2 more sources

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

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